Entry Nos. 14100–14199
100 Garrison-Morton entries in this range.
1952 CE
#14100
Tissue culture studies of the proliferative capacity of cervical carcinoma and normal epithelium.
A cell biologist at Johns Hopkins Hospital, Gey propagated the HeLa cell line from Henrietta Lacks' cervical tumor. This cell line, which maintained a continuous growth phase, was the first immortal human cell line to…
2013 CE
#14101
The haplotype-resolved genome and epigenome of the aneuploidy HeLa cancer cell line.
Adey and colleagues sequenced the haplotype-resolved whole genome of the HeLa cancer cell line. This showed a highly rearranged region at chromosome 8q24.21, where an integration locus of the HPV (human papillomavirus…
2017 CE
#14102
The role of the WI-38 cell strain in saving lives and reducing morbidity.
In 1961 "Hayflick developed the first normal human diploid cell strains for studies on human aging and for research use throughout the world. Prior to his seminal research, all cultured cell lines were immortal and an…
1963 CE
#14103
Recurrent Dupuytren's contracture.
Hueston described Dupuytren's diathesis, including early onset, bilateral involvement, postive family history, and presence of ectopic lesions. He noted that patents presenting Dupuytren's diathesis experience more se…
2021 CE
#14104
Morbid undercurrents: Medical subcultures in postrevolutionary France.
"During the 1790s and beyond, medicine left the somber halls of universities, hospitals, and learned societies and became profoundly politicized, inspiring a whole panoply of different—often bizarre and shocking…
1835 CE
#14105
Nouvelles recherches sur la structure de la peau.
Beschet emphasized "the relevance of anatomic investigation to dermatologic problems" (Crissey and Parish, Dermatology and syphilology of the nineteenth century, 117). In this book the authors first described the anat…
2022 CE
#14106
Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models.
Abstract: "We evaluated the performance of a large language model called ChatGPT on the United States Medical Licensing Exam (USMLE), which consists of three exams: Step 1, Step 2CK, and Step 3. ChatGPT performed at o…
2022 CE
#14107
Genetics of atavism.
Abstract: "Atavisms have attracted people’s attention for a long time. First, atavisms excited their imagination and created fertile ground for myths and superstitions. With the development of science, atavisms …
1980 CE
#14108
The striking resemblance of high-resolution G-banded chromosomes of man and chimpanzee.
Chimpanzees are the closest primates genetically to humans. In this paper the authors demonstrated the genetic changes that differentiated humans from chimpanzees. By comparing human and chimpanzee chromosomes the aut…
2002 CE
#14109
La dermatologie en France. Edited by Daniel Wallach and Gérard Tilles
"Realisé à l'initiative de la Société française d'histoire de la dermatologie. Rédigé par 76 auteurs représentant la communauté dermatologique franç…
1938 CE
#14110
Artificial fever produced by physical means; its development and application.
Perhaps the most comprehensive study of the application of pyrotherapy in the treatment of a wide variety of diseases, including syphilis. For syphilis in particular the treatment was replaced by penicillin, developed…
2001 CE
#14111
Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia.
The authors showed that the experimental drug (STI571) Imatinib, sold under the brand names Gleevec and Glivec, 1) was well tolerated and had very significant antileukemic activity in patients with chronic myeloid leu…
2011 CE
#14112
Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia.
Carl H. June and colleagues proved that the ‘concept’ of CAR T-cell therapy developed by them, was a very promising and viable alternative in specific recalcitrant cancers. They showed that their novel in-…
1485 CE
#14113
De balneis et thermis naturalibus omnibus Italiae.
The second printed book on balneology. Savonarola took a skeptical approach to the subject, relying on his own observations and rejecting the notion that baths owed their virtues to occult or supernatural properties. …
2012 CE
#14114
Cardiovascular and neurological causes of sudden death after ischaemic stroke.
Hachinski and Sörös discovered that the control of the heart by the brain is asymmetric, with the fight/flight (sympathetic) response controlled by the right hemisphere and the rest and digest (parasympathet…
1974 CE
#14115
Multi-infarct dementia. A cause of mental deterioration in the elderly.
The authors showed that contrary to the prevailing view that most dementias were caused by hardened brain arteries (cerebral atherosclerosis), most were multi-infarct dementias—dementias caused by multiple, smal…
1987 CE
#14116
Cognitive and neurologic findings in subjects with diffuse white matter lucencies on computed tomographic scan (Leuko-Araiosis).
"Abstract: As part of a prospective clinicopathologic study, a cohort of 105 "normal" elderly volunteers was investigated with computed tomographic scans, psychometric testing (Extended Scale for Dementia [ESD]) and n…
1773 CE
#14117
A treatise on the kinkcough. With an appendix. Containing an account of hemlock, and its preparation.
Probably the first book on whooping cough, proceeding Watt's book by 40 years. Butter proposed hemlock as a treatment for whooping cough. Digital facsimile from Google Books at this link. (Thanks to Webb Dordick for t…
1785 CE
#14118
Catalogue raisonné des ouvrages qui ont été publiés sur les eaux minérales en général et sur celles de la France en particulier, avec un notice doutes des eaux minérales de ce royaume, et un tableau des différens degrés de température de celles qui son thermales.
The earliest bibliography of mineral springs. Digital facsimile from Google Books at this link. (Thanks to Webb Dordick for this reference.)
1786 CE
#14119
Manuel pour le service des malades, ou précis des connoissances nécessaires aux personnes chargées du soin des malades, femmes en couche, enfans nouveaux-nés, &c.
The first French book on nursing. Digital facsimile of the 1787 edition from the Internet Archive at this link. (Thanks to Webb Dordick for this reference.)
1782 CE
#14120
Unterricht für Krankenwärter zum Gebrauch öffentlicher Vorlesungen.
The first German book on nursing--a manual of instructions for male nurses. Digital facsimile from Google Books at this link. (Thanks for Webb Dordick for this reference.)
1703 CE
#14121
L'art de faire les raports en chirurgie, où l'on ensiegne la pratique, les formules & le stile le plus en usage parmi les chirurgiens commis aux rapports; avec un extrait des arrest, statuts & reglemens faits en consequence.
Digital facsimile from Google Books at this link. (Thanks to Webb Dordick for this reference.)
2021 CE
#14122
Augustin Cabanès (1862-1928): Clinicien de l'histoire ou vulgaire anecdotier?
1562 CE
#14123
Bullein's bulwarke of defẽce againste all sicknes, sornes, and woundes that dooe daily assaulte mankinde, which bulwarke is kepte with Hillarius the Gardiner, Health the Phisician, with their chyrurgian to helpe the wounded soldiors. Gathered and practised frō the moste worthie learned, both old and newe: to the greate comforte of mankinde. Doen by Williyam Bulleyn, and ended this Marche, Anno Salutis 1562.
A work of medical humanism written while Bullein and his wife were in prison for debts. Bullein was the only writer of medical works in English in the sixteenth century to employ the dialogue form, allowing the physic…
1829 CE–1830 CE
#14124
Flora medica: Containing coloured delineations of the various medicinal plants, admitted into the London, Edinburgh, and Dublin pharmacopoeias; with their natural history, botanical descriptions, medical and chemical properties, &c. &c.; together with a concise introduction to botany; a copious glossary of botanical terms and a list of poisonous plants, &c. &c. Edited by a member of the Royal college of physicians, and fellow of the Linnaean society; with the assistance of several eminent botanists; in two volumes.
Digital facsimile from Google Books at this link.
1856 CE
#14125
Glances and glimpses; or fifty years social, including twenty years professional life.
The autobiography of the first woman to practice medicine professionally in the United States. Digital facsimile from U.S. National Library of Medicine at this link.
1912 CE
#14126
Technique chirurgicale infantile: Indications opératoires, opérations courantes.
Ombrédanne improved surgical techniques for the correction of undescended testicles, cleft palate and penile hypospadias in children.
1976 CE
#14127
The eradication of smallpox.
Henderson's paper in the October 1976 issue of Scientific American was one of the first published announcements of the completion of the eradication of smallpox. Illustrating the iconic photograph of a mother holding …
2007 CE
#14128
Beyond the White House, waging peace, fighting disease, and building hope.
President Carter devoted half of this book to Guinea worm disease, nature of the illness, its epidemiology, its cause and the current importance from a public health and human suffering standpoint. Carter's leadership…
1996 CE
#14129
"From proteins to proteomes: Large scale protein identification by two-dimensional electrophoresis and amino acid analysis.
Foundation of Proteomics. Order of authorship in the original publication: Wilkins, Pasquali, ...Hochstrasser. "Abstract: Separation and identification of proteins by two-dimensional (2-D) electrophoresis can be used …
1851 CE
#14130
Traité complet des maladies vénériennes. Clinique iconographique de l'Hôpital des vénériens. Recueil d'observations, suivies de considérations pratiques sur les maladies qui ont été traitées dans cet hôpital.
Ricord's extensive work with veneral diseases at the Hopital du Midi includes 66 hand-colored ithographs illustrating a multitude of conditions at various levels of infection in both sexes. The illustrations were draw…
1997 CE
#14131
Proteome research: New frontiers in functional genomics.
Order of editorship in the original publication: Wilkins, Williams, Appel, Hochstrasser. "Recent advances in two-dimensional gel electrophoresis, protein microanalytsis and bioinformatics have made the large-scale, sy…
1842 CE
#14132
Die angeborenen chirurgischen Krankheiten des Menschen in Abbildungen dargestellt und durch erläuternden Text erklärt. Mit fünfhundert vierundsiebzig Figuren auf vierunddreissig Kupfertafeln in Folio. 2 vols.
A treatise on malformations of particular interest to surgeons, including facial clefts, urogenital anomalies, anorectal atresias, parasitic twins, and limb duplications. Digital facsimile of the text, without the vol…
1835 CE
#14133
Ueber die Vermehrung der Pflanzen-Zellen durch Theilung. Eine Inaugural-Dissertation welche zur Erlangung der Doctor-Würde in der Medicin und Chirurgie welche / unter dem Präsidium von Hugo Mohl; vorlegt August Wilhelm Winter.
In his doctoral thesis Mohl reported his discovery of the multiplication of cells by division, later known as mitosis. Digital facsimile from Bayerische StaatsBibliothek at this link.
2011 CE
#14134
Crystal structure of the β2 adrenergic receptor–Gs protein complex.
Kobilka and colleagues published the crystal structure of a beta-2 receptor forming a complex with the G protein coupled receptor. This was the first time that a complete complex of an active receptor and it's Gs prot…
2011 CE
#14135
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor.
Using X ray crystallographic techniques and electron microscopy, Kobilka (Nobel Prize 2012) and colleagues described the very complex nucleotide exchange and interactions at the molecular level of the alpha subunit of…
1863 CE
#14136
Observations in midwifery. As also The countrey midwifes opusculum or vade mecum
First edition of this work written in English in the 17th century, privately published in 1863, supposedly in an edition of 100 copies, from a manuscript then owned by Blenkinsop. Willughby has been characterized as "…
2009 CE
#14137
Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-alpha-1,3-galactose.
Discovery of mammalian meat allergy (MMA) or Alpha-gal syndrome (AGS), also called Alpha-gal allergy, a type of meat allergy characterized by delayed onset of symptoms (3-8 hours) after ingesting mammalian meat. The a…
1946 CE
#14138
Die Tänze der Bienen.
Von Frisch discovered the waggle dance, a particular figure-eight dance of honey bees by which successful foragers can communicate information with other members of their colony about the direction and distance to pat…
2023 CE
#14139
Social signal learning of the waggle dance in honey bees.
The authors showed that the complex waggle dance, previously thought to be an inborn trait, is partly learned by young bees as they observe more experienced bees. Abstract: "Honey bees use a complex form of spatial re…
1983 CE
#14140
Mammalian beta-adrenergic receptors. Structural differences in beta 1 and beta 2 subtypes revealed by peptide maps.
Lefkowitz and colleagues showed that there are two different types of beta receptors, distinguishing them as Beta-1 and Beta-2. They noticed that each has specific pharmacological characteristics. Order of authorship …
1959 CE
#14141
Factors affecting the activity of muscle phosphorylase b kinase.
In 1992 Krebs and Fischer were awarded the Nobel Prize in Physiology or Medicine "for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism." Digital facsimile from PubMe…
1969 CE
#14142
Isolation of adenyl cyclase from Escherichia coli.
Lipmann and Tao isolated, purified, and characterized biochemically an enzyme which they called "adenyl cyclase." They stated that this enzyme is responsible for producing "cyclic AMP" in E. coli. Digital facsimile fr…
1977 CE
#14143
Resolution of some components of adenylate cyclase necessary for catalytic activity.
Goodman shared the 1994 Nobel Prize in Physiology or Medicine with Martin Rodbell "for their discovery of G-proteins and the role of these proteins in signal transduction in cells." In this paper Goodman and Ross show…
1978 CE
#14144
Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.
Gilman and colleagues showed that G proteins are in the cell membrane and are stimulated once a ligand (adrenaline) binds the adrenergic receptor. This system can then activate adenyl cyclase to form cyclic AMP. Digit…
1883 CE
#14145
A book of medical discourse in two parts. Part first: Creating of the cause, prevention, and cure of infantile bowel complains, from birth to the close of the teething period, or till after the fifth year. Part second: Containing miscellaneous information concerning the life and growth of beings; the beginning of womanhood; also, the cause, prevention, and cure of many of the most distressing compains of women and youth of both sexes.
Crumpler was the first Black woman to receive a medical degree in the United States. Digital facsimile from the Internet Archive.
2018 CE
#14146
Cloning of Macaque monkeys by somatic cell nuclear transfer.
The authors at the Chinese Academy of Sciences in Shanghai reported the first cloning of a non-human primate. Full text available from cell.com at this link. Order of authorship in the original publication: Liu, Cai..…
1905 CE
#14147
An anatomical, experimental, and clinical study of acute phlegmons of the hand.
"Kanavel produced the classic paper on infection in Surgery, Gynecology and Obstetrics in 1905. In that paper, he described the anatomy and clinical study of acute infections of the hand. This clearly changed the cour…
2011 CE
#14148
Remedy and reaction: The peculiar American struggle over health care reform.
"Winner of the 2011 American Publishers Awards and Scholarly Excellence (PROSE) in the Government and Politics category, as given by the Association of American Publishers. Read an interview with Paul Starr on the Yal…
1992 CE
#14149
