Facets

1900 CE

#6110

Cancer of the uterus: Its pathology, symptomatology, diagnosis, and treatment. Also the pathology of diseases of the endometrium.

Includes first clinical and pathological study of hyperplasia of the endometrium. Cullen is remembered eponymically for “Cullen’s sign”, a discoloration of the skin about the umbilicus, regarded as a…

1872 CE

#7831

Descriptive catalogue of the teratological series in the Museum of the Royal College of Surgeons of England.

Digital facsimile from the Internet Archive at this link.

1989 CE

#6832

Hautkrankheiten. 5 Jahrhunderte wissenschaftlicher Illustration / Skin Diseases. 5 Centuries of Scientific Illustration.

Bilingual text, richly illustrated in color, on the great illustrated works in the history of dermatology.

1971 CE

#13958

Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs.

In 1982 Vane shared the Nobel Prize in Physiology or Medicine with Sune Bergström and Bengt Samuelsson for "their discoveries concerning prostaglandins and related biologically active substances."

1953 CE

#2578.11

‘Actively acquired tolerance’ of foreign cells.

Proof of Burnet and Fenner’s theory of immunity. For their discovery of acquired immunological tolerance Medawar and Burnet (No. 2578.7) shared the Nobel Prize in 1960.

1927 CE

#3088

"Methodology of examining bone marrow in live patients, with haemopoietic disease."

Needle puncture of bone marrow biopsy. (In Russian.) German account in Folia haemat. (Lpz.), 1929, 38, 233-40. English translation from the German in Bick, Classics of orthopaedics, 339-44.

1944 CE

#2659.2

“Folic acid” a tumor growth inhibitor.

Inhibition of tumor growth by a folic acid concentrate. With R. Lewisohn, D. Laszlo. These workers later (Proc. Soc. exp. Biol. N. Y., 1944, 56, 144-45) obtained similar results with xanthopterin.

1953 CE

#1138.1

3:5:3'-Triiodothyronine. I. Isolation from thyroid gland and synthesis.

Discovery of the second thyroid hormone, triiodothyronine. Digital facsimile from PubMedCentral at this link.

1965 CE

#3666.4

A “new” antigen in leukemia sera.

(Order of authorship in the original publication: Blumberg, Alter, Visnich.) Discovery of Australia antigen, hepatitis B antigen, Aa, later called HBsAg. Blumberg received half of the Nobel Prize for Medicine in Biolo…

1960 CE

#11219

A bibliography of internal medicine: Selected diseases.

Literature on "selected diseases" presented in chronological order, beginning with auricular fibrillation and ending with trichinosis, emphasizing cardiovascular and metabolic diseases.

2016 CE

#10185

A biographical history of endocrinology.

1913 CE

#3192.1

A biological classification of pneumococci by means of immunity reactions.

Dochez and Gillespie differentiated four types of pneumococci.

1896 CE

#5530.1

A case of blastomycetic dermatitis in man.

Gilchrist’s description of blastomycosis (“Gilchrist’s disease”, “Busse-Buschke disease”, Nos. 5529.1 and 5529.2), is an important contribution to the knowledge of the infectious gr…

1839 CE

#4259

A case of enlargement from melanoid tumour of the prostate gland, in a child of five years of age.

Sarcoma of the prostate was first recorded by Stafford.

1889 CE

#4096

A case of erythema with remarkable nodular thickening and induration of skin, associated with intermittent albuminuria.

Erythema elevatum diutinum (“Bury’s disease”).

1879 CE–1880 CE

#4076

A case of multiple tumors of the skin accompanied by intense pruritis.

First description of prurigo nodularis. In 1909 J. N. Hyde (Diseases of the skin, Philadelphia, p. 174) was responsible for its present name and for the eponym “Hyde’s disease”.

1879 CE

#4560.1

A case of partial epilepsy, apparently due to a lesion of one of the vasomotor centres of the brain.

“Sturge–Weber syndrome” – association of a port-wine nevus in the skin of the face with a vascular abnormality of the meninges on the same side. See No. 4605.2.

1925 CE

#4151

A case of relapsing non-suppurative nodular panniculitis, showing phagocytosis of subcutaneous fat-cells by macrophages.

Weber–Christian disease (see No. 4152).

1911 CE

#4685

A case of suprarenal apoplexy.

Waterhouse–Friderichsen (WFS) syndrome (see also Nos. 4679, 4686).

1925 CE

#3862

A case of tetany treated with parathyrin.

First use of parathyroid hormone in the treatment of tetany.

1925 CE

#3872

A case of virilism associated with a suprarenal tumour: recovery after its removal.

Records the first removal (by P. Sargent) of an adrenal cortical tumor. This was followed by disappearance of the heterosexual symptoms, thus establishing the relationship of sexual abnormality and adrenal tumors.

1926 CE

#4608

A classification of the tumors of the glioma group on a histogenetic basis with a correlated study of prognosis.

From 1922 to 1925 Bailey undertook extensive pathological and histological studies of brain tumors, and based on cellular configuration, he created a classification system of thirteen categories. In 1927 he reduced th…

1880 CE

#4078

A clinical study of hydroa.

First description of dermatitis herpetiformis (“Duhring’s disease”; see No. 4083).

1931 CE

#4611.2

A clinical study on positional nystagmus in cases of brain tumour.

1915 CE

#1162.1

A contribution to the physiology of lactation.

Gaines demonstrated the action of the pituitary in lactation.

1924 CE

#1238

A description of the glomerular circulation in the frog’s kidney and observations concerning the action of adrenalin and various other substances upon it.

Richards made many experiments concerning the secretion of urine. Among other things he collected and analysed the fluid from a single glomerulus; his work confirmed the theories of Ludwig and Cushny.

1727 CE

#7061

A discourse concerning the causes and effects of corpulency, together with the method for its prevention and cure.

The first book on obesity in English.

1760 CE

#7060

A discourse on the nature, causes, and cure of corpulency. Illustrated by a remarkable case, Read before the Royal Society, November 1757. And now first published.

Digital facsimile from Google Books at this link.

1964 CE

#14197

A familial disorder of uric acid metabolism and central nervous system dysfunction.

Lesch-Nyhan syndrome, a rare inherited disorder that affects about 1 in 380,000 live births. In their summary the authors described this as a new "syndrome consisting of hyperuricemia, mental retardation, choreoatheto…

1926 CE

#5782.1

A further report on cancer of the breast, with special reference to its associated antecedent conditions.

First modern case-control study.

2011 CE

#7132

A guide to obesity and the metabolic syndrome: Origins and treatment.

2015 CE

#8253

A historical perspective on evidence-based immunology.

Thoroughly documented and well-illustrated history, with a timeline and bibliography for each chapter.

1982 CE

#3910

A history of endocrinology.

A detailed illustrated history, tracing the development of knowledge from ancient times to the present. Includes biographical notes on the important pioneers in the field and chronological tables. Revised and updated …

1965 CE

#2581.6

A history of immunization.

1989 CE

#2581.14

A history of immunology.

Carefully documented, well-written, analytical history from the ancient world to c. 1975 by an expert researcher in the field. Includes biographical dictionary of notable contributors, list of “seminal discoveri…

1970 CE

#2581.8

A history of medical bacteriology and immunology.

1988 CE

#10452

A history of the Imperial Cancer Research Fund 1902-1986.

"The author takes a broad perspective and provides a comparative framework by discussing the changing relationship between the ICRF and the medical profession, government, and other charities, notably the Cancer Resea…

1996 CE

#12794

A history of transplantation immunology.

Written by one of the founders of the science.

1986 CE

#13974

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma.

Isolation of the first human tumor suppressor gene. Order of authorship in the original publication: Friend, Bernards, Rogeli, Weinberg, Rapaport, Albert, Dryja.

2013 CE

#13691

A medical history of skin: Scratching the surface. Edited by Jonathan Reinarz and Kevin Siena.

1908 CE

#3528.1

A method of performing abdomino-perineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon.

Miles devised the operation of abdomino-perineal resection.

1843 CE

#3259

A nasal operation for the removal of a large tumour filling up the entire nostril and extending to the pharynx.

Removal of a fibrous growth from the nostril by division of the nasal and maxillary bones, July 8, 1841. Preliminary note in the same journal, 1842, 3, 257.

1950 CE

#2352

A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.

1934 CE

#5045

A new antigen of B. typhosus. Its relation to virulence and to active and passive immunisation.

Vi antigens first described.

1932 CE

#3923.1

A new error of tyrosine metabolism: tyrosinosis, intermediary metabolism of tyrosine and phenylalanine.

1922 CE

#4150

A new eruptive fever associated with stomatitis and ophthalmia; report of two cases in children.

“Stevens-Johnson syndrome”, a generalized eruption, continued fever, inflamed buccal mucosa, and severe purulent conjunctivitis. B.A. Thomas (Brit. med. J., 1950, 1, 1393) believes this to be merely a seve…

1982 CE

#11058

A new subtype of human T-cell leukemia virus (HTLV-II) associated with a T-cell variant of hairy cell leukemia.

Order of authorship in the original publication: Kalyanaraman, Sarngadharan,... Gallo. Discovery by Gallo of HTLV-II, which like HTLV-I, is carcinogenic. (Thanks to Juan Weiss for this entry and its interpretation.)

1951 CE

#4154.4

A new syndrome combining developmental anomalies of the eyelids, eyebrows and nose root with pigmentary defects of the iris and head hair with congenital deafness.

“Waardenburg’s syndrome”.

1954 CE

#3924.3

A new syndrome: progressive familial infantile cerebral dysfunction associated with unusual urinary substance.

Maple syrup urine disease described. With P. L. Hurst and J. M. Craig.

1984 CE

#12664

A new type of papillomavirus DNA, its presence in genital cancer biopsies and in cell lines derived from cervical cancer.

Zur Hausen and colleagues discovered HPV18 as a cause of cervical cancer. With the discovery of HPV18, and HPV16, which zur Hausen and team discovered in 1983, zur Hausen discovered the viruses causing about 75% of hu…