1840–1849

1846 CE

#13418

Catalogue des Livres composant la Bibliothèque de feu … Gilbert Breschet.

Digital facsimile from Google Books at this link.

1846 CE

#11213

Catalogue of the Library of the Royal Medical and Chirurgical Society of London. [By Benjamin Robert Wheatley].

Digital facsimile from the Internet Archive at this link. Between 1907 and 1909 the Royal Medical and Chirurgical Society of London became one of 17 English medical societies that joined to form the Royal Society of M…

1846 CE

#5652

Circular. Morton’s Letheon.

Unaware of Crawford Long’s results with ether, Morton, having been informed of the anesthetic effects of ether by Charles T. Jackson, promoted its anesthetic effects. To do so he published the above circular, in…

1846 CE

#2031

De historia medicamentorum.

1846 CE

#1459

Der Tastsinn und das Gemeingefühl. In: Wagner’s Handwörterbuch der Physiologie, Braunschweig, 3, Abt. 2, 481-588.

English translation of Tastsinn, Academic Press, 1978.

1846 CE

#14337

Disquisitiones de structura protuberantia annularis sive pontis Varolii. Untersuchungen über den Bau des Hirnknotens oder der Varoli’schen Brucke. Text and atlas.

Stilling’s great work on the pons Varolii, the structure that links the brain to the spinal cord, includes the first accurate description of the red nucleus (superior olive), a structure in the midbrain involved…

1846 CE

#5338

Entozoon in the superficial part of the extensor muscles of the thigh of the hog. Abstract

First description of trichinosis in the pig.

1846 CE

#3368.1

Erfahrungen über die Krankheiten des Gehöres und ihre Heilung.

Schmalz demonstrated the clinical significance of Weber’s hearing test (see No. 3368). He was a student of Weber.

1846 CE

#8918

Geological observations on South America. Being the third part of the geology of the voyage of the Beagle.

The third and last of Darwin's geological reports on the Beagle voyage. In it he described the pampas, the plateaus and the Andres, showing how they had been gradually pushed up in the way that Charles Lyell surmised …

1846 CE

#5651

Insensibility during surgical operations produced by inhalation.

William T. G. Morton used ether as an anesthetic for the first time on 16 October 1846 during at operation by John Collins Warren to remove a benign angioma under the jaw of a patient at Massachusetts General Hospital…

1846 CE

#4527

Klinische Ergebnisse.

Includes (p. 75) a classic description of facial hemiatrophy – “Romberg’s disease”.

1846 CE

#2902

Lectures illustrative of various subjects in pathology and surgery.

Page 361 contains the first description of intermittent claudication in man. This was first reported (in the horse) by “Boullay” [?J. Bouley] in Arch. gén. Méd.,1831, 27, 425. P. 186: Brodie'…

1846 CE

#2755.1

Lectures on subjects connected with clinical medicine, comprising disease of the heart. Second edition, 2 vols.

Includes (vol. 2, pp. 373-79) a classic description of coronary thrombosis, although not using the term. The patient was Thomas Arnold, the educationist, and the report was signed by Joseph Hodgson and by S. Bucknill,…

1846 CE

#413

Lehrbuch der Anatomie des Menschen.

Hyrtl’s Lehrbuch passed through 22 editions and was translated into the principal modern languages.

1846 CE

#4528

Lehrbuch der Nervenkrankheiten des Menschen. Bd. 1.

Romberg inaugurated the modern era in the study of diseases of the nervous system. His Lehrbuch is the first formal treatise in this field. On p. 795 is to be found the original description of “Romberg’s s…

1846 CE

#13739

Medical notes on China.

Wilson served as Inspector of Hospitals and Fleets from 1841 to 1843 onboard the Minden, a British hospital ship deployed in China at Chusan and Hong Kong at the end of 1841 to treat casualties in the First Opium War …

1846 CE

#5650.3

Mesmerism in India, and its practical application in surgery and medicine.

Esdaile performed a variety of surgical operations on Hindus, upon many of whom he appears successfully to have induced hypnotic anesthesia. However, his similar attempts with Europeans were not so successful.

1846 CE

#2295

Microscopic examination of some of the principal tissues of the animal frame, as observed in the tongue of the living frog, toad, etc.

Waller observed the penetration and migration of leucocytes through the endothelial vessel walls.

1846 CE

#2756

Observations on some cases of permanently slow pulse.

Stokes’s celebrated account of heart block with syncopal attacks – the Stokes–Adams syndrome (see also No. 2745). Stokes was most interested in the diagnostic value of this condition. The paper is re…

1846 CE

#5861

On a luminous appearance of the human eye, and its application to the detection of disease of the retina and posterior part of the eye.

While a student at the London Hospital, Cumming, by shading the eye of a fellow student from the light, was able to look directly into it and obtain both the retinal reflex and the white light from the entrance of the…

1846 CE

#930

On the capacity of the lungs, and on the respiratory functions, with a view of establishing a precise and easy method of detecting disease by the spirometer.

Invention of the spirometer, making possible the determination of the vital capacity of the lungs. Hutchinson used the spirometer while evaluating candidates for life insurance as a physician for Brittania Life. Parti…

1846 CE

#11558

On the disorders of the cerebral circulation; and on the connection between affections of the brain and diseases of the heart.

"Burrows was the first to indicate that the effects of cerebral anemia could be produced not only by obvious anemia itself, but also from a fall in blood pressure. He carried out some of the earliest studies of the ph…

1846 CE

#4325.1

On the microscopical character of mollifies ossium.

Report of the histological examination of bone material containing multiple myeloma from the patient described by Macintyre (No. 4327).

1846 CE

#1319

On the nerves of the uterus.

Beck showed that in man the thoracic sympathetic chain receives communications from the last cervical, thoracic, and upper 1 or 2 lumbar ganglia.

1846 CE

#3062.1

Particulars of a case in which enormous enlargement of the spleen and liver, together with dilatation of all the blood vessels of the body, were found coincident with a peculiarly altered condition of the blood.

Leukemia diagnosed during life as the result of a blood examination.

1846 CE

#11724

Physical education and the preservation of health.

An expanded version of a lecture first delivered and published as a pamphlet in 1830. This is the first edition in book form, and one of the first American works on the value of exercise for the preservation of health…

1846 CE

#4039

Pilzbildung in der Pityriasis versicolor.

Eichstedt discovered Pityrosporum orbiculare, fungus of pityriasis versicolor (“Eichstedt’s disease”).

1846 CE

#4637

Primi cenni sulla corea elettrica.

First description of electric chorea, “Dubini’s chorea”, the myoclonic form of epidemic encephalitis.

1846 CE

#2612.1

The nature and treatment of cancer.

The earliest account of the recognition of fragments of malignant tissue. Digital facsimile from Google Books at this link.

1846 CE

#79

The works. Edited with an introduction and notes by George Gulliver.

Hewson was a pupil of the Hunters. In 1769 his memoir on the lymphatics in fishes won for him the Copley Medal of the Royal Society. See also Nos. 863, 1102. The editor of this edition provided a detailed historical i…

1846 CE

#8587

The young stethoscopist; or, the student's aid to auscultation.

Through this book Bowditch established the stethoscope as a diagnostic tool in America. Digital facsimile from the Medical Heritage Library, Internet Archive, at this link.

1846 CE

#6856

Therapeutisches Taschenbuch für Homöopathische Aerzte.

Frequently reprinted. "Bönninghausen's Therapeutic Pocketbook of 1846 was the first homeopathic repertory to grade individual remedies by their strength of relationship with each symptom, and each other. This so-…

1846 CE

#4937

Traitement moral, hygiène et education des idiots…

Séguin was the first to outline a complete plan for the training of mental defectives. A pupil of Itard and Esquirol, he subsequently worked in America, where he published Idiocy: and its treatment by the physi…

1846 CE

#7310

U. S. Patent No. 4848. The United States of America. To all to whom these Letters Patent shall come.... November 12, 1846.

U.S. Patent No. 4848, issued to Charles T. Jackson and William T. G. Morton on November 12, 1846 for the discovery of sulfuric ether as a surgical anesthetic. This was the first truly significant medical patent ever i…

1846 CE

#2323

Ueber die Ansteckung und Verbreitung der Scrophelkrankheit bei Menschen durch den Genuss der Kuhmilch.

Klencke showed the possibility of the transmission of tuberculosis to man by cow’s milk. In 1843 he succeeded in inoculating rabbits with tuberculosis.

1846 CE

#4038

Ueber die Krätzmilben des Menschen, ihre Entwicklung und ihr Verhältniss zur Krätze.

1846 CE

#808

Ueber die peristaltische Bewegung des Oesophagus, nebst einigen Bemerkungen über diejenigen des Darms.

Includes (pp. 76-77) a description of what is probably the first perfusion of the isolated heart.

1846 CE–1847 CE

#5026

Practical remarks on the continued fevers of Great Britain, and on the generic distinctions between enteric fever and typhus.

Introduction of the term “enteric fever”, a term for typhoid. Ritchie carefully differentiated the symptoms of typhus and typhoid.

1846 CE–1848 CE

#331

Lehrbuch der vergleichenden Anatomie. 2 vols.

Vol. 2 was published in 1846; Vol. 1 in 1848. Digital facsimiles of both vols. from Biodiversity Heritage Library at this link. Siebold was the author of Vol. 1, on invertebrates; he introduced the taxa Arthropoda and…

1846 CE–1848 CE

#3912.1

Several specimens of cystine exhibited, with the particulars of two cases in which this deposit occurred in the urine.

Cystinuria described.

1846 CE–1849 CE

#13859

Descriptive catalogue of the pathological specimens contained in the museum of the Royal College of Surgeons of England. 5 vols.

Vol.1: General pathology -- Vol.2: Pathology of the blood, and organs of locomotion -- Vol.3 Pathology of the organs of digestion, absorption and circulation -- Vol.4: Pathology of the respiratory and urinary organs, …

1846 CE–1849 CE

#544

The microscopic anatomy of the human body, in health and disease.

First English textbook on microscopical anatomy. His description of the concentric corpuscles of the thymus (p. 9) led to the term “Hassall’s corpuscles”.

1847 CE

#329.1

A description of the characters and habits of troglodytes gorilla, a new species of orang from the Gaboon River, by Thomas S. Savage; Osteology of the same by Jeffries Wyman.

First description of the gorilla. Savage, an American physician/clergyman, worked extensively as a missionary physician in Africa. Digital facsimile from Google Books at this link.

1847 CE

#7602

A descriptive catalogue of the Anatomical Museum of the Boston Society for Medical Improvement.

Digital facsimile from the Internet Archive at this link.

1847 CE

#5660

A history of the discovery of the application of nitrous oxide gas, ether, and other vapours, to surgical operations.

In 1844 Wells, a Hartford dentist, successfully used nitrous oxide as a dental anesthetic. To publicize his discovery, he arranged a demonstration at Harvard Medical School in January 1845, but this proved a fiasco. W…

1847 CE

#5862

A manual of the principles and practice of ophthalmic medicine and surgery.

The last important English work on opthalmology published before the invention of the ophthalmoscope. Jones did not appreciate the prototype ophthalmoscope devised by Charles Babbage, and shown to him in 1847. After t…

1847 CE

#4417.1

A treatise on fractures in the vicinity of joints and on certain forms of accidental and congenital dislocations.

The first important work on fractures by an Irish author. It includes the description of “Smith’s fracture”. In his chapter “On fractures of the bones of the forearm in the vicinity of the wris…

1847 CE

#5657.1

A treatise on the inhalation of the vapour of ether, for the prevention of pain in surgical operations; containing a numerous collection of cases in which it has been applied, with the names of the operators; history of the discovery - description of the apparatus - method of preparing the ether - remarks as to the time when the operation should commence, etc., etc., etc.

The first textbook of ether anesthesia, published in March, 1847. Robinson, a British dentist, was the first to use anesthesia in England, after receiving information from Henry Jacob Bigelow and Francis Boott. Digita…

1847 CE

#770

Beiträge zur Kenntniss des Einflusses der Respirationsbewegungen auf den Blutlauf im Aortensystem.

Ludwig changed Poiseuille’s hemodynamometer into the kymograph by the addition of a float and caused this float to write on a recording cylinder. Abridged English translation in Ruskin (No. 3160.1).

1847 CE

#994

Beobachtung einer tödlichen Peritonitis, als Folge einer Perforation des Wurmfortsatzes.

Description of “Gerlach’s valve”, sometimes seen at the orifice of the appendix.