Facets

1936 CE

#7346

Quantitative und qualitative Untersuchungen über den Sympathicusstoff*. Zugleich XIV. Mitteilung über humorale Übertragung der Herznervenwirkung Ausgeführt mit Unterstützung der -Stiftung.

In this paper Loewi proved that the cardioexcitatory neurotransmitter of the sympathetic nerves is adrenaline, or actually noradrenaline.

1994 CE

#12638

Reader in the history of aphasia from [Franz] Gall to [Norman] Geschwind. Edited by Paul Eling.

1959 CE

#14242

Receptive fields of single neurones in the cat's striate cortex.

Also: Hubel & Wiesel, Receptive fields, binocular interaction and functional architecture in the cat's visual cortex, J. Physiol., 160, 1962, 106-154. In 1981 Hubel and Wiesel shared half of the Nobel Prize in Physiol…

1825 CE

#4618

Recherches cliniques propres à démontrer que la perte de la parole correspond à la lésion des lobules antérieurs du cerveau.

Classic account of aphasia. Bouillaud was the first to suggest that injuries of the frontal lobe were a cause of aphasia.

1840 CE

#768

Recherches expèrimentales sur le mouvement des liquides dans les tubes de très petits diamètres.

Poiseuille’s law of the flow of liquids in tubes – fundamental in blood viscosimetry. Abstract; complete monograph in Mém. Acad. roy. Sci. (Paris), 1846, 9, 433-544. First book-form edition, Paris, …

1910 CE–1911 CE

#5384

Recherches experimentales sur le typhus exanthématique.

Nicolle demonstrated the transmission of typhus by the body louse Pediculus corporis. He also produced the disease in monkeys and guinea-pigs by the injection of infected blood. Preliminary communication in C. R. Acad…

1844 CE

#1264

Recherches expérimentales sur les fonctions du nerf spinal, étudié spécialement dans ses rapports avec le pneumogastrique.

1824 CE

#1493

Recherches expérimentales sur les propriétés et les fonctions du système nerveux, dans les animaux vertébrés.

Experimental proof that vision depends on the integrity of the cerebral cortex. See No. 1391 for his first paper on the subject. Partial English translation in von Bonin, Some papers on the cerebral cortex, Springfiel…

1842 CE

#1397

Recherches physiologiques et cliniques sur le liquide céphalo-rachidien ou cérébro-spinal. 1 vol. and atlas.

“Foramen of Magendie” described.

1800 CE

#597

Recherches physiologiques sur la vie et la mort.

When Volta questioned the validity of experiments claiming to show responsiveness of an ex vivo heart, devoid of blood flow and nervous connections, Bichat obtained permission to experiment upon the freshly killed bod…

1938 CE

#11179

Recherches sur l'embryologie du système central de l'homme.

1828 CE

#767

Recherches sur la force du coeur aortique.

Poiseuille was the first after Stephen Hales to make any important addition to the knowledge of the physiology of circulation. In his graduation thesis, above, he described a “hemodynamometer” invented by …

1883 CE

#502.1

Récherches sur la maturation de l’oeuf, la fécondation et la division cellulaire.

This work extended Hertwig’s work on fertilization (No. 495) down to the level of chromosomes, which were clearly visible in Ascaris after the sperm and egg united.

1860 CE

#776

Recherches sur le pouls au moyen d’un nouvel appareil enregistreur le sphygmographe.

Invention of the modern sphygmograph. Also published in C.R. Acad. Sci. (Paris), 1860, 51, 281-309. Preliminary paper in same journal, 1860, 50, 634-37.

1866 CE

#12358

Recopilación histórico-bibliográfica de la circulación de la sangre en el hombre y los animales.

Digital facsimile from bdh-rd.bne.es at this link.

1930 CE

#1577

Reflex action. A study in the history of physiological psychology.

Reprinted, New York, Hafner, 1964.

1880 CE–1882 CE

#826

Regarding the action of hydrate of soda, hydrate of ammonia, and hydrate of potash on the ventricle of the frog’s heart.

“Ringer’s solution”

1973 CE

#14241

Regulation of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase activity in human fibroblasts by lipoproteins.

Goldstein and Brown discovered that human cells have low-density lipoprotein (LDL) receptors that remove cholesterol from the blood and that when LDL receptors are not present in sufficient numbers, individuals develo…

1979 CE

#14247

Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamine.

With CA Gruetter, BK Barry, DB McNamara, DY Gruetter, PJ Kadowitz. In 1998 Ignarro shared the Nobel Prize in Physiology or Medicine with Robert F. Furchgott and Ferid Murad "for their discoveries concerning nitric oxi…

1861 CE

#1400

Remarques sur le siège de la faculté du langage articulé, suivie d’une observation d’aphémie (perte de la parole).

Broca claimed the third left frontal convolution of the brain as the center of articulate speech – a point now disputed. He was first to trephine for a cerebral abscess diagnosed by this theory of localization o…

1987 CE

#1588.23

Renal physiology: People and ideas.

A collective work on the history of renal physiology with thematic chapters by the editors and other prominent investigators.

1963 CE

#8149

Representation of a Function by its Line Integrals, with Some Radiological Applications.

Cormack showed that changes in tissue density could be computed from x-ray data. Because of limitations in computing power no machine was constructed during the 1960s. Cormack's papers generated little interest until …

1897 CE

#12288

Researches on the circulation time in organs and on the influences which affect it.

This was a continuation of researches undertaken by Stewart for the Goodsir Prize Essay at the University of Edinburgh (1892). His autograph manuscript for the 1892 essay was digitized by the university at made availa…

1869 CE

#1404

Researches on the physiology of the cerebellum.

Mitchell, leading American neurologist of his time, performed over 350 experiments upon the cerebellum. He emphasized its co-ordinating function, first postulated by Flourens, and he proposed his “augmentor&rdqu…

1893 CE

#837

Researches on the structure and function of the mammalian heart.

Kent also discovered the atrioventricular bundle (“bundle of Kent”), a narrow band of muscle between the auricles and ventricles of the heart. Its purpose is to act as a bridge for contractile impulses bet…

1977 CE

#14143

Resolution of some components of adenylate cyclase necessary for catalytic activity.

Goodman shared the 1994 Nobel Prize in Physiology or Medicine with Martin Rodbell "for their discovery of G-proteins and the role of these proteins in signal transduction in cells." In this paper Goodman and Ross show…

1922 CE

#961

Respiration.

An account of the work of the Oxford School of Physiology, in particular the Pike’s Peak expedition (No. 957). Second edition, 1935, with J. G. Priestley.

1996 CE

#7779

Respiratory physiology: People and ideas, edited by John B. West.

1968 CE

#12282

Response to exercise after bed rest and after training.

Order of authorship in the original publication: Saltin, Blomqvist, Mitchell, Johnson, Wildenthal, Chapman. Chapman planned the Dallas Bed Rest and Training Study, which defined the degree to which the level of habitu…

1984 CE

#14265

Restoration of circadian behavioral rhythms by gene transfer in Drosophila.

"At The Rockefeller University in the early 1980s, Young and his two lab members, Ted Bargiello and Rob Jackson, further investigated the circadian period gene in Drosophila. They constructed segments of recombinant D…

1974 CE

#7453

Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.

Doherty and Zinkernagel discovered how a class of white blood cells known as T cells kill virus-infected cells in the body, and so present the spread of viruses. In 1998 Zinkernagel and Doherty were awarded the Nobel …

1906 CE

#4630

Révision de la question de l’aphasie; la troisième circonvolution frontale gauche ne joue aucun rôle spécial dans la fonction du langage.

Marie disputed Broca’s claim that the third left frontal convolution of the brain is the speech center. He classified aphasia into three groups: anarthria (defects of articulation), Broca’s (motor) aphasia…

1970 CE

#2660.23

RNA-dependent DNA polymerase in virions of Rous sarcoma virus.

Discovery of reverse transcriptase. "In 1969, Temin and a postdoctoral fellow, Satoshi Mizutani, began searching for the enzyme that was responsible for the phenomenon of viral RNA being transferred into proviral DNA.…

1952 CE

#13938

Rôle des cations bivalents dans l'induction du développement du prophage par les agents reducteurs.

Lwoff gave the name "prophage" to the form in which the genome of the bacteriophage is perpetuated in lysogenic bacteria. The bacteriophages produced by these bacteria, known as temperate bacteriophages, can therefore…

1953 CE–1956 CE

#86.1

Sämtliche Werke. 6 vols. in 10.

1984 CE

#1588.20

Science and medicine in France. The emergence of experimental physiology, 1790-1855.

1918 CE–1973 CE

#82

Sebrané spisy. Opera omnia. Tom. 1-12.

Purkynĕ was Professor of Physiology at Breslau and Prague. Eminent as physiologist and microscopist, he was first to use the microtome. See Kruta, V. J.E. Purkynĕ, Physiologist. A short account of his contributions&he…

1966 CE

#1588.2

Selected readings in the history of physiology. Second edition, revised.

These readings extend from Aristotle to contemporary writers; they give access to many classical works that might otherwise be unobtainable to students of the history of physiology. Foreign material is translated into…

1947 CE

#1534

Sensory mechanisms of the retina: with an appendix on electroretinography.

An account of twenty years’ work on the electrical responses of the retina, a discussion of visual purple and visual violet, and an exposition of Granit’s hypothesis of colour vision. His researches have d…

1958 CE

#2578.25

Separation and isolation of fractions of rabbit gamma-globulin containing the antibody and antigenic combining sites.

In 1972 Porter shared the Nobel Prize in Physiology or Medicine with G.M. Edelman (No. 2578.39) "for their discoveries concerning the chemical structure of antibodies."

1910 CE

#245.2

Sex-limited inheritance in Drosophila.

Morgan demonstrated sex-limited inheritance. In 1933 Morgan was awarded the Nobel Prize in Physology or Medicine "for discoveries elucidating the role that the chromosome plays in heredity." See also Nos. 245.3, 246, …

1976 CE

#7454

Single-channel currents recorded from membrane of denervated frog muscle fibres.

In 1991 Neher and Sakmann were awarded the 1991 Nobel Prize in Physiology or Medicine for "their discoveries concerning the function of single ion channels in cells." They were also awarded the prize for the invention…

1987 CE

#13931

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells.

In 2007 Capecchi shared the 2007 Nobel Prize in Physiology or Medicine with Martin J. Evans and Oliver Smithies "for their discoveries of principles for introducing specific gene modifications in mice by the use of em…

1902 CE

#1576

Some apostles of physiology.

Well illustrated, and finely printed, but dated history, by a pupil of Ludwig. See No. 629.

1942 CE

#532

Some aspects of early human development.

Report of the youngest normal implanted fertilized human ovum, fertilization age about 7 1/2 days. Hertig and Rock published a more detailed study in Contr. Embryol. Carneg. Instn. 1945, 31, 65-84.

1929 CE

#2716

Some different types of essential hypertension; their course and prognosis.

The Keith-Wagener-Barker classification of hypertension. With N. W. Barker.

1971 CE

#6890

Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae.

Nathans showed that the restriction enzyme discovered by Hamilton Smith cleaved SV40 DNA into 11 specific pieces. Nathans and his student Kathleen Danna wrote: "The availability of pieces of SV40 DNA from specific sit…

1959 CE

#13242

Speech and brain mechanisms.

1980 CE

#13228

Speech and speech disorders in Western thought before 1600.

1980 CE

#14186

Speech disorder in nineteenth century Britain. The history of stuttering.