Response to exercise after bed rest and after training.

Order of authorship in the original publication: Saltin, Blomqvist, Mitchell, Johnson, Wildenthal, Chapman. Chapman planned the Dallas Bed Rest and Training Study, which defined the degree to which the level of habitual physical activity determines cardiovascular capacity, and measured the extent to which prolonged bed rest causes cardiovascular deterioration. The findings provided a firm physiological rationale for early ambulation of patients after acute myocardial infarction and quantified the potential benefits of exercise rehabilitation.

Several follow-up studies to this research occurred and appeared in various journals. See Jere H. Mitchell, Benjamin D. Levine, Darren K. McGuire,"The Dallas Bed Rest and Training Study revisited after fifty years," Circulation, 140 (2019) 1293-1295.