Facets

1906 CE

#2594

Das Theobald Smithsche Phänomen der Serum-Ueberfindlichkeit. In Gedenkschr. f.d. verstorb. Generalstabsarzt… von Leuthold, 1, 153-72

The “Theobald Smith phenomenon” was not reported by Smith but communicated by him to Ehrlich. Later Otto published details of the results obtained in his study of the phenomenon.

1860 CE

#4049

Das umschriebene Eczem. Eczema marginatum. In Virchow’s Handbuch der spec. Path. u. Therap., 3, 1 Abt., 361-63.

Complete description of tinea cruris (eczema marginatum), first described by Bärensprung in 1854.

1577 CE

#7990

De arte medica infantium libri quatuor. Quorum duo Priores de tuenda eorum sanitate, posteriores de curandis morbis agunt.

An early illustrated work on pediatrics. The three parts of his book deal with the management of the nurse and her milk, the care and feeding of the new-born, and diseases of children, including skin diseases, and cha…

1564 CE

#2581.99

De catarrho commentarius.

Summer catarrh (hay fever) first described. Partial English translation in No. 2241.

1758 CE–1763 CE

#3878

De cranii ustione in pertinacioribus capitis vitiis. In his: Ratio medendi in nosocomio practico, 6, 239-287. 8 vols.

Haen provided the first description of amenorrhea in connection with a pituitary tumor. He recorded the case history of a young woman suffering from amenorrhea as well as many neurological symptoms assumed to result f…

1794 CE

#3879

De curandis hominum morbis epitome. Liber V.

Frank was the first to define diabetes insipidus (pp. 38-67).

1603 CE

#3805

De generatione stultorum. In his Opera, 2, 174-82.

Paracelsus was the first to note the coincidence of cretinism and endemic goitre. It was not until the 19th century that the possibility of the occurrence of cretinism in adults was entertained. Partial English transl…

1883 CE

#14211

De l'Atténuation des virus, avec la collaboration de MM. Chamberland, Roux et Thuillier. Quatrième Congrès international d'hygiène et de démographie. Séance du 5 Septembre 1882.

In his seminal 1880 paper, Sur les maladies virulentes, et en particulier sur la maladie appelée vulgairement choléra des poules, GM-2537, Pasteur developed the idea of a protective inoculation by attenu…

1875 CE

#7064

De l'obésité: étiologie, thérapeutique et hygiène. Thèse présentée et soutenue le 12 Aout 1875.

Primarily a summary of research on the subject to date. Worthington was an American from Cincinnati who received his M.D. in Paris in 1876, and practiced there until 1879, when he returned to the U.S.A. A geneological…

1879 CE

#3472

De l’ablation des tumeurs de l’estomac par la gastrectomie.

First gastrectomy for carcinoma; unsuccessful.

1902 CE

#2590

De l’action anaphylactique de certains venins.

First full description of the phenomenon of “anaphylaxis,” the name of which was coined by Richet. Abbreviated English translation in Bibel, Milestones of immunology (1988). In 1913, Richet was awarded the…

1907 CE

#2599

De l’anaphylaxie en général et de l’anaphylaxie par la mytilocongestine en particulier.

In 1913 Richet was awarded the Nobel Prize in Physiology or Medicine "in recognition of his work on anaphylaxis."

1907 CE

#2596

De l’anaphylaxie et de l’anti-anaphylaxie vis-à-vis du sérum de cheval.

“Anti-anaphylaxis” was the term given by Besredka and Steinhardt to the specific desensitization of sensitized animals.

1880 CE

#2492.1

De l’extension de la théorie des germes à l’étiologie de quelques maladies communes.

In this study of furunculosis (“boils”) and osteomyelitis Pasteur left the first recognizable descriptions of staphylococcus and streptococcus. The term streptococcus had been coined by Billroth in 1874; h…

1860 CE

#4050

De l’hypertrophie générale du système sébacé.

First description of keratosis follicularis.

1888 CE

#5034

De l’immunité contre le virus de la fièvre typhoöde conférée par des substances solubles.

Experimental antityphoid inoculation.

1865 CE

#168

De la chevelure comme caractéristique des races humaines.

Pruner-Bey did the first important work on the classification of races according to texture and shape in section of hair. Digital facsimile from Persee.fr at this link.

1875 CE

#3940

De la glycosurie ou diabète sucré; son traitement hygiénique.

Bouchardat used the fermentation test, polariscope and copper solutions for the detection of diabetes; he substituted fresh fats for carbohydrates, advised the avoidance of milk and alcohol, invented gluten bread and …

1889 CE

#4097

De la psorospermose folliculaire végétante.

Dyskeratosis follicularis was so well described by Darier that it is universally known as “Darier’s disease”. J. C. White also described it (see No. 4093) and the first description is accredited to H…

1586 CE

#3417

De medica historia mirabili.

An early history of diseases, with extensive sections on ophthalmology (ff. 66-77) and urology (ff. 260-271). Lib. IV, Cap. iii, page 196 contains the first recorded case of gastric ulcer. Lib. VI. cap. iii contains t…

1609 CE

#3806

De mirabili strumas sanandi.

An early historical record of goitre which du Laurens maintained was contagious. Du Laurens was at one time physician to Henri IV.

1616 CE

#534.52

De monstrorum caussis, natura, & differentiis libri duo.

One of the earliest classifications of deformities, Liceti’s work was still under review in works on malformation in the 19th century. Includes both real and imaginary cases. The first of many illustrated editio…

1572 CE

#3980

De morbis cutaneis, et omnibus corporis humani excrementis tractatus.

The first systematic textbook on diseases of the skin. English translation by R. L. Sutton Jr, Kansas City, Missouri, Lowell Press, 1986. Mercuriali enjoyed a great reputation in his day; he wrote on many medical subj…

1714 CE

#3981

De morbis cutaneis. A treatise of diseases incident to the skin.

Turner may be regarded as the founder of British dermatology. His book, the first English text on the subject, gives a good idea of contemporary knowledge of skin diseases. Turner began his career as a barber surgeon,…

1795 CE

#2609.1

De morbis vasorum absorbentium corporis humani.

Soemmerring noted an association between pipe smoking and cancer of the lip (p. 109).

1857 CE

#3456

De polypis oesophagi atque de tumore ejus generis primo prospere exstirpato.

First operation for tumor of the esophagus.

1632 CE

#2273

De recondita abscessuum natura.

The first textbook of surgical pathology. It treats of all kinds of swelling under the term “abscess” and describes neoplasms of the genital organs and sarcoma of bones. Tumors of the breast are classified…

1752 CE

#3424.1

De tumore scirrhoso trium cum quadrante librarum glandulae parotidis extirpato.

First description of parotid tumor.

1624 CE

#2971

De tumoribus praeter naturam libri quinque. Ex instructissima Bibliotheca Ranchiniana eruti, & publici iuris facti, cura & studio Henric Gras...Accessit Ioannis Saportae Tractatus de lue venerea.

IN 1554 Saporta gave the earliest description of an aortic aneurysm. Many years after Saporta's death Henri Gras of Lyon discovered the manuscript of Saporta's book, and edited it for publication. Digital facsimile fr…

1553 CE

#5073

De tumoribus praeter naturam.

This treatise on tumors includes (p. 194) the first known description of an epidemic disease resembling scarlet fever. This was a malady prevalent in Italy, and was commonly called rossania or rossalia. Ingrassia was …

1824 CE

#2606

De tumoribus praeter naturam. In his Opera omnia, ed. cur. C.G. Kühn. 7, 705-32.

Galen’s classification of tumors persisted for more than 1,000 years. He considered neoplasms to be due to an excess of black bile, which solidified in certain sites. He advocated purges to dissolve the black bi…

1766 CE

#2527.99

De variolis et morbillis commentarius.

The first medical description of smallpox was written by Rhazes, about the year 910… The above work is the first edition of the Arabic text with a parallel Latin translation by the English pharmacist and schola…

1666 CE

#1230

De viscerum structura exercitatio anatomica.

Includes (pp. 71-100) his essay, De renibus, in which he described the uriniferous tubules and the “Malpighian bodies”. The great detail and clarity of Malpighi’s description was unsurpassed until Bo…

1896 CE

#3840.1

Deaf-mutism and goitre.

Pendred syndrome, a genetic disorder leading to congenital bilateral (both sides) sensorineural hearing loss and goitre with euthyroid or mild hypothyroidism (decreased thyroid gland function).

1998 CE

#8785

Death of medicine in Nazi Germany: Dermatology under the Swastika. Edited by A. Bernard Ackerman.

1895 CE

#6100

Deciduoma malignum.

First case of choriocarcinoma reported in North America.

1820 CE

#3812

Découverte d’un nouveau remède contre le goitre.

Coindet is usually regarded as the first to administer iodine in cases of goitre, with beneficial results. It had previously been prepared from seaweed by B. Courtois in 1812 (Ann. Chim. (Paris), 1813, 88, 304-10), an…

1998 CE

#12112

Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in the Tlr4 gene.

Order of authorship in the original paper: Poltorak, Smirnova...Beutler. The authors, led by Beutler, showed that mice that harbor a mutation of the gene which codes for the production of the Toll-like receptor TLR4 q…

1993 CE

#13472

Defining criteria for autoimmune diseases (Witebsky's postulates revisited).

In 1993 Rose and Bona revised Witebsky's postulates "based on direct evidence from transfer of pathogenic antibody or pathogenic T-cells, indirect evidence based on reproduction of the autoimmune disease in experiment…

2009 CE

#14137

Delayed anaphylaxis, angioedema, or urticaria after consumption of red meat in patients with IgE antibodies specific for galactose-alpha-1,3-galactose.

Discovery of mammalian meat allergy (MMA) or Alpha-gal syndrome (AGS), also called Alpha-gal allergy, a type of meat allergy characterized by delayed onset of symptoms (3-8 hours) after ingesting mammalian meat. The a…

1966 CE

#2578.36

Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction.

Lymphokines (MIF). Simultanteously discovered by Barry R. Bloom (1937-) & B. Bennett. See Science, 1966, 153, 80-82.

1817 CE

#3988

Delineations of cutaneous diseases exhibiting the characteristic appearances of the principal genera and species comprised in the classification of the late Dr. Willan; and completing the series of engravings begun by that author.

Bateman, the pupil of Willan, continued his teacher’s classification of skin diseases. The above work is notable for its 72 colored plates. Strictly speaking it is the first atlas of dermatology, as Willan&rsquo…

1938 CE

#5308.1

Demonstratión de un treponema en el borde activo un caso de pinto de las manos y pies y en la linfa de ganglios superficiales (reporte preliminar).

B. Saenz, J. Grau Triana, and J. Alfonso Armenteros indicated that pinta is caused by a treponeme, T. carateum.

1888 CE

#2620.2

Demonstration der durch Impfung von Hund auf Hund erzeugten Carcinomknötchen.

A tumor transplant from dog to dog was reported by Wehr.

1897 CE

#2002

Demonstration eines mit Röntgenstrahlen behandelten Falles von Naevus pigmentosus pilosus.

First use of x rays for deep irradiation therapy.

1908 CE

#1181

Der Bau der Uterusschleimhaut des geschlechtsreifen Weibes besonderer Berücksichtigung der Menstruation.

First definite description of the cyclical changes in the endometrium, which were shown to be a normal physiological process.

1898 CE

#3952

Der Diabetes mellitus.

Naunyn devoted his life to the study of metabolism in diabetes and in diseases of the liver and pancreas. This is his most significant work. He was a co-founder of the Archiv für experimentelle Pathologie.

1865 CE

#2618

Der Epithelialkrebs namentlich der Haut. 1 vol. and atlas.

Thiersch, Professor of Surgery at Erlangen, and inventor of the method of skin grafting which bears his name, also made an important contribution to the knowledge of the histogenesis of cancer. He disproved Virchow&rs…

1858 CE

#6045

Der Gebärmutterkrebs.

In this work Wagner presented the first important contribution to the knowledge of the gross pathology of uterine cancer.

1827 CE

#14285

Der Leichnam des Menschen in seinen physischen Verwandlungen nach Beobachtungen und Versuchen.

The human corpse in its physical transformations according to observations and experiments.