Facets

1894 CE

#643

Le mouvement.

Marey, like Muybridge (No. 650-51), was a pioneer in the use of serial pictures as a method of studying the mechanics of locomotion. English translation, 1895.

2009 CE

#10775

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation.

Gero Hütter and co-authors reported the first long-term remission or "cure" of HIV/AIDS in a human. The patient, Timothy Ray Brown also known as "The Berlin Patient" also suffered from myeloid leukemia and underw…

2019 CE

#14014

Machine learning identification of surgical and operative factors associated with surgical expertise in virtual reality simulation.

"Abstract "Importance Despite advances in the assessment of technical skills in surgery, a clear understanding of the composites of technical expertise is lacking. Surgical simulation allows for the quantitation of ps…

1996 CE

#11110

Making PCR: A story of biotechnology.

1972 CE

#10505

Medical geography: Techniques and field studies. Ediited by N. D. McGlashan

Chapter 5: "Computers and mapping in medical geography" by R. W. Armstrong appears to be one of the earliest reviews of this subject.

1994 CE

#9718

Molecular politics: Developing American and British regulatory policy for genetic engineering, 1972-1982.

2020 CE

#14043

Patents on life: Religious, moral, and social justice aspects of biotechnology and intellectual property. Edited by Thomas C. Berg, Roman Cholij, and Simon Ravenscroft.

2022 CE

#14106

Performance of ChatGPT on USMLE: Potential for AI-assisted medical education using large language models.

Abstract: "We evaluated the performance of a large language model called ChatGPT on the United States Medical Licensing Exam (USMLE), which consists of three exams: Step 1, Step 2CK, and Step 3. ChatGPT performed at o…

1990 CE

#14340

Phage antibodies: Filamentous phage displaying antibody variable domains.

Working in the Laboratory of Molecular Biology at Cambridge University, Winter became interested in the idea that all antibodies have the same basic structure, with only small changes making them specific for one targ…

2004 CE

#8137

Primer of robotic & telerobotic surgery. Edited by Garth H. Ballantyne, Jacques Marescaux, and Pier Cristoforo Giulianotti.

1959 CE

#12655

Programs with Common Sense. IN: Mechanisation of thought processes, Proceedings of the Symposium of the National Physics Laboratory, pages 77-84.

"Programs with Common Sense was probably the first paper on logical AI, i.e. AI in which logic is the method of representing information in computer memory and not just the subject matter of the program. The paper was…

1993 CE

#7182

Radiological oncologists: The unfolding of a medical specialty.

1984 CE

#11363

Readings in medical artificial intelligence: The first decade. Edited by William Clancey and Edward H. Shortliffe.

1959 CE

#6908

Reasoning foundations of medical diagnosis.

The beginning of the development of clinical decision support systems (CDSS) — interactive computer programs, or expert systems, designed to assist physicians and other health professionals with decision making …

1978 CE

#9720

Recombinant DNA: The untold story.

1960 CE

#12654

Recursive functions of symbolic expressions and their computation by machine, Part 1.

The original paper on LISP, the first programming language designed for symbolic computation, which made the development of artificial intelligence programming possible. Part 2 was never published. Digital text from j…

1963 CE

#8149

Representation of a Function by its Line Integrals, with Some Radiological Applications.

Cormack showed that changes in tissue density could be computed from x-ray data. Because of limitations in computing power no machine was constructed during the 1960s. Cormack's papers generated little interest until …

2020 CE

#13332

Revolutionary therapies: How the California Stem Cell Program saved lives, eased suffering - and changed the face of medicine forever.

2009 CE

#13335

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche.

Order of authorship in the original publication: Sato, de Vries, .... Clevers. Clevers and postdoc Toshiro Sato took adult stem cells from the mouse intestine and created the first mini-guts they called organoids&mdas…

1987 CE

#13931

Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells.

In 2007 Capecchi shared the 2007 Nobel Prize in Physiology or Medicine with Martin J. Evans and Oliver Smithies "for their discoveries of principles for introducing specific gene modifications in mice by the use of em…

1982 CE

#10046

Splicing life: A report on the social and ethical issues of genetic engineering with human beings.

Digital facsimile from the Internet Archive at this link.

2002 CE

#13598

Stem cells and the future of regenerative medicine.

In 2001 this report cited the following diseases with high prevalence in the United States as likely candidates for stem cell research: Cardiovascular Disease: 58 million U.S. patients Automimmune Disease: 30 million …

1939 CE

#3098

Studies on leukemia with the aid of radioactive phosphorus.

Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley Nationa…

1896 CE

#2001

Sur les radiations émises par phosphorescence.

The discovery of radioactivity – research stimulated by Roentgen’s discovery of x rays. In 1903 Becquerel received half of the Nobel Prize in Physics 1903 "in recognition of the extraordinary services he h…

1953 CE

#14290

Switching systems as mechanized brains.

Written in the earliest days of automatic switching systems when few electronic computers existed, Meszar's paper raised the question of whether certain aspects of human thought are computable and others are not. Mesz…

1987 CE

#13940

Targeted correction of a mutant HPRT gene in mouse embryonic stem cells.

Smithies discovered, simultaneously with Mario Capecchi and Martin Evans, the technique of homologous recombination of transgenic DNA with genomic DNA, a much more reliable method of altering animal genomes than previ…

2018 CE

#13049

Telemedicine and health technologies: A guide for mental health professionals.

"...Telepsychiatry and Health Technologies: A Guide for Mental Health Professionals is a practical, comprehensive, and evidence-based guide to patient-centered clinical care delivered in whole or in part by technologi…

1975 CE

#7522

Telemedicine: Explorations in the use of telecommunications in health care.

The first book on telemedicine, with contributions by 18 authors, including Kenneth T. Bird. In the final chapter the editors summarize telemedicine programs then operational in the United States. The book also includ…

1991 CE

#8138

Telepresence: Dextrous procedures in a virtual operating field.

The first teleoperated surgery. Funded by the U.S. Dept. of Defense, the first prototype of a telesurgery robot was developed at Stanford Research International (SRI) (Menlo Park, CA) and called the Green Telepresence…

1949 CE

#7992

The Army Medical Library research project at the Welch Medical Library.

One of the first reports on one of the earliest projects in automating information retrieval, the expression for which was coined by Calvin Mooers the following year. At this early date electronic computers were not y…

2013 CE

#13284

The California Institute for Regenerative Medicine. Science, governance, and the pursuit of cures

The California Institute for Regenerative medicine was the first state-fund institution that provided stable, in-state funding on a very large scale for biomedical research. "The California Institute for Regenerative …

2009 CE

#11399

The coming of age of artificial intelligence in medicine.

Order of authorship in the original publication: Patel, Shortliffe, Stefanelli, Szolovits, Berthold, Bellazzi, Abu-Hanna. "Abstract: This paper is based on a panel discussion held at the Artificial Intelligence in Med…

1977 CE

#12031

The construction of molecular cloning vehicles. II. A multipurpose cloning system.

Order of authorship in the original publication Bolivar, Rodriguez, Betlach...Boyer...The authors describe the composition and molecular construction of pBR-322 (named after Bolivar and Rodriguez) and call it "the mos…

2011 CE

#13319

The delivery of regenerative medicines and their impact on healthcare. Edited by Catherine D. Prescott and Dame Julia Polak.

1916 CE

#14094

The differentiation of cells as a criterion for cell identification, considered in relation to the small cortical cells of the thymus.

First use of the term "stem cells" in English. Digital facsimile from rupress.org at this link.

1963 CE

#12428

The distribution of colony-forming cells among spleen colonies.

Evidence that stem cells are capable of self-renewal. (Order of authorship in the original publication: Siminovitch, McCullch, Till). Digital facsimile from tspace.library.utoronto.ca at this link.

1981 CE

#9728

The DNA story: A documentary history of gene cloning.

2015 CE

#11368

The genealogy of a gene: Patents, HIV/AIDS, and race.

"Myles Jackson uses the story of the CCR5 gene to investigate the interrelationships among science, technology, and society. Mapping the varied “genealogy” of CCR5—intellectual property, natural sele…

2006 CE

#9722

The genetics revolution: History, fears and future of a life-altering science.

2020 CE

#13776

The human gene editing debate.

"Provides a history of the debate about gene editing, a summary of the ethics, and a proposal for moving forward. Re-conceptualizes the historical discussion about gene editing in the context of today's widespread use…

2010 CE

#9459

The introduction of numerical methods to assess the effects of medical interventions during the 18th century: a brief history.

An outstanding bibliographical survey available online from the James Lind Library at this link.

1963 CE

#7947

The MEDLARS story at the National Library of Medicine.

Digital facsimile from the Internet Archive at this link.

1895 CE

#9320

The mental development of the child and the race.

A central text in the development of social psychology in North America; now also considered a pioneering study of adaptive learning, and in this sense a precursor to research in artificial intelligence. Digital facsi…

1949 CE

#14289

The mind of mechanical man.

Jefferson’s paper on the differences between electronic computers and the human brain inspired Alan Turing to respond with his famous paper, “Computing machinery and intelligence” (1950), which intro…

2013 CE

#11978

The NCBI handbook, 2nd edition.

Available online from ncbi.nlm.nih.gov at this link. "The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM) at the U.S. National Institutes of Health, is a lead…

2013 CE

#13729

The NCBI handbook, 2nd edition.

https://www.ncbi.nlm.nih.gov/books/NBK143764/ "The National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM) at the U.S. National Institutes of Health, is a leader in t…

2009 CE

#11355

The quest for artificial intelligence.

A history of artificial intelligence in general, including medical applications, from the 18th century onward by a pioneer of artificial intelligence.

1980 CE

#11488

The seeds of artificial intelligence: SUMEX-AIM.

A semi-popular and extensively illustrated summary of research on artificial intelligence in medicine at Stanford Medical School as directed by Edward A. Feigenbaum, Stanley N. Cohen, Carl Djerassi, and Elliott C. Lev…

1993 CE

#8618

The uses of life: A history of biotechnology.

1986 CE

#10201

The Visible Human Project.

https://www.nlm.nih.gov/research/visible/visible_human.html "The Visible Human Project® is an outgrowth of the NLM's 1986 Long-Range Plan. It is the creation of complete, anatomically detailed, three-dimensional r…