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Garrison-Morton-Norman History of Medicine
SMITHIES, Oliver (1925 – 2017)

SMITHIES, Oliver (1925 – 2017)

1925 – 2017

1 entries in the GMN corpus.

Image source Douglas A. Lockard · Science History Institute , Douglas A. Lockard. · CC BY-SA 3.0

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1987 CE

#13940

Targeted correction of a mutant HPRT gene in mouse embryonic stem cells.

SMITHIES, Oliver (1925 – 2017)
SMITHIES, Oliver (1925 – 2017) DOETSCHMAN, Thomas C. GREGG, Ronald G. & et al.

Smithies discovered, simultaneously with Mario Capecchi and Martin Evans, the technique of homologous recombination of transgenic DNA with genomic DNA, a much more reliable method of altering animal genomes than previ…