BOLÍVAR ZAPATA, Francisco Gonzalo (1948 – )
1948 –
3 entries in the GMN corpus.
1977 CE
#10964
Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin.
Order of authorship in the original paper: Itakura, Hirose, Crea..., Bolivar, Boyer. Synthesis of the gene for somatostatin (growth hormone-inhibiting hormone (GHIH). This was the first demonstration of a foreign gene…
1977 CE
#12031
The construction of molecular cloning vehicles. II. A multipurpose cloning system.
Order of authorship in the original publication Bolivar, Rodriguez, Betlach...Boyer...The authors describe the composition and molecular construction of pBR-322 (named after Bolivar and Rodriguez) and call it "the mos…
1979 CE
#13980
Expression in Escherichia coli of chemically synthesized genes for human insulin (plasmid construction / lac operon / fused proteins / radioimmunoassay / peptide purification).
GOEDDEL, David V. (1951 – ) KLEID, Dennis G. CREA, Roberto BOLÍVAR ZAPATA, Francisco Gonzalo (1948 – ) & et al.
Working at Genentech, Kleid and Goeddel and colleagues were the first scientists to apply genetic engineering techniques, incorporating chemically synthesized DNA encoding human insulin into E. coli, that expressed, a…