Facets

1959 CE

#11560

Digital recording of electrocardiographic data for analysis by a digital computer.

This is probably the earliest paper on the use of computers to analyze electrocardiograms. The abstract: "A corrected orthogonal 3-lead system has been used to record electrocardiograms directly from patients at Veter…

1916 CE

#1904

Digitaliswirkung am isolierten Vorhof des Frosches.

An important analysis of the action of digitalis on the isolated heart.

1930 CE

#1920

Digoxin, a new digitalis glucoside.

Isolation of digoxin from Digitalis lanata.

1915 CE

#2894

Diseases of the arteries, including angina pectoris. 2 vols.

Includes his suggestion of the aortic genesis of angina pectoris, and (vol. 2, p. 368) his mechanical theory of cardiac pain in coronary occlusion.

1910 CE

#11752

Diseases of the heart and aorta.

The first comprehensive monograph on cardiology written and published in the United States. Hirschfelder interned under William Osler at Johns Hopkins, and became Hopkins's first full-time cardiologist. Digital facsim…

1898 CE

#2808

Diseases of the heart and the aorta.

Includes among many other valuable descriptions, the description of the "Gibson murmur" also called the "machinery murmur"

1867 CE

#10603

Diseases of the heart: Their diagnosis and treatment.

The first medical book, as distinct from a pamphlet, that was written and published in California. See Shapiro, "California's 'first' medical book. David Wooster's Diseases of the heart (1867)," Calif. Med., 108 (1968…

1908 CE

#2826

Diseases of the heart.

Chapter 30 of the third edition (1914) includes Mackenzie’s classic description of the clinical picture of “nodal rhythm” (auricular fibrillation). Reprinted in Willius & Keys, Cardiac classics, 1941…

1735 CE

#3052

Disquisitio medica et philologica de variolis et anthracibus.

Werlhof gave a classic description of purpura haemorrhagica (“Werlhof’s disease”).

1884 CE

#1572

Doctrines of the circulation.

1982 CE

#12244

Doppler ultrasound in cardiology: Physical principles and clinical applications.

1861 CE

#2762

Du double souffle intermittent crural, comme signe de l’insuffisance aortique.

The double intermittent murmur over the femoral arteries, diagnostic of aortic insufficiency, has become known as “Duroziez’s sign.” Partial English translation in No. 2241.

1877 CE

#2780

Du rétrécissement mitral pur.

First description of congenital mitral stenosis, “Duroziez’s disease.”

1876 CE

#2777

Du rhythme cardiaque appelé bruit de galop, de son mécanisme et de sa valeur séméiologique.

Analysis of “gallop rhythm.” Partial English translation in No. 2241 and No. 3160.1.

1889 CE

#3130

Du sang et de ses altérations anatomiques

Includes (pp. 614-751) an important account of chlorosis; Hayem, by his accurate observation, placed knowledge of the disease on a firm basis.

1889 CE

#2798

Du sphygmomanomètre et de la mésure de la pression artérielle chez l’homme à l’état normale et pathologique.

Potain devised a simple portable air sphygmomanometer for blood-pressure estimation.

1921 CE

#3001

Du traitement des varices par les injection coagulantes, concentrées de sels de quinine.

Injection of quinine urethane for the treatment of varicose veins.

2001 CE

#10335

Dying in the City of the Blues: Sickle cell anemia and the politics of race and health.

"Set in Memphis, home of one of the nation's first sickle cell clinics, Dying in the City of the Blues reveals how the recognition, treatment, social understanding, and symbolism of the disease evolved in the twentiet…

1938 CE

#2867

Effects of induced oxygen want in patients with cardiac pain.

Diagnosis of cardiac pain. With A. L. Barach and H. G. Bruenn.

1891 CE

#2908.1

Ein Beitrag zur Lehre von der Gefässnaht.

Jassinowsky experimented with arterial sutures on animals. His thesis, Die Arteriennaht: Eine experimentell-chirurgische Studie, Dorpat, 1889, was an experimental-surgical study of the subject.

1924 CE

#3016

Ein durch die Trendelenburgsche Operation geheilter Fall von Embolie der Art. pulmonalis.

First successful surgical treatment of pulmonary embolism, a procedure suggested by Trendelenburg in 1908 (see No. 3012).

1900 CE

#890

Ein einfaches Verfahren zur directen Schätzung der Färbestärke des Blutes.

Tallqvist’s hemoglobin scale.

1913 CE

#3014

Ein Fall operierter Embolie der Arteria femoralis.

Key performed his first successful embolectomy on December 4, 1912, and reported it to a meeting of the Svenska Läkaresällskapet on January 28, 1913. See also his review in Ergebn. Chir. Orthop.,1929, 22,1-94.

1866 CE

#3119

Ein Fall von Anaemia splenica bei einem Kinde

First reported case of (infantile) splenic anemia.

1871 CE

#2982

Ein Fall von Aneurysma der Leberarterie.

Quincke observed aneurysm of the hepatic artery in 1870.

1872 CE

#2774

Ein Fall von Endocarditis ulcerosa puerperalis mit Pilzbildungen im Herzen (Mycosis endocardii).

Heiberg suggested the microbic nature of endocarditis. He described what appeared to him to be the mycelia of Leptothrix in the vegetations of a case of ulcerative endocarditis.

1870 CE

#3066

Ein Fall von Leukämie mit Erkrankung des Knochenmarkes.

Neumann was the first to note changes in the bone marrow in leukemia, and he proposed the term “myelogenous leukemia”.

1872 CE

#2775

Ein Fall von Pulsus bigeminus nebst Bemerkungen über die Leberschwellungen bei Klappenfehlern und über acute Leberatrophie.

First clear description of pulsus bigeminus. Translated in Willius & Keys, Cardiac classics, 1941, pp. 590-99.

1878 CE

#2781

Ein Fall von thrombotischen Verschlusse einer der Kranzarterien des Herzens.

First description of coronary thrombosis with diagnosis before death. English translation of original report, Amer. J. Cardiol, 1978, 42, 849-52.

1930 CE

#3144.1

Ein hochwirksamer, injizierbarer Leberextrakt.

Gänsslen introduced an injectable liver extract in the treatment of pernicious anemia.

1857 CE

#3064.1

Ein neuer Fall von Leukämie.

Acute leukemia first described.

1872 CE

#3124

Eine eigenthumliche Form von progressiver perniciöser Anämie.

In his account of progressive pernicious anemia, Biermer was first to describe the retinal haemorrhages. He was at one time accredited with the first description of pernicious anemia ; later it was shown that Addison …

1931 CE

#3091

Eine klinisch brauchbare Bestimmungsmethode der Blutumlaufszeit mittels Decholininjektion.

The decholin method for estimation of circulation time. With J. Deutsch and Z. Brull.

1901 CE

#1754

Eine Methode zur Unterscheidung der verschiedenen Blutarten, im besonderen zum differentialdiagnostischen Nachweise des Menschenblutes.

Uhlenhuth was the first to use precipitins in medico-legal tests for human blood.

1974 CE

#3161.4

Einführung in die Geschichte der Haematologie.

Thirteen contributions edited by Boroviczény, H. Schipperges, and E. Seidler. Includes chronological table of events in the history of medicine and a bibliography.

1850 CE

#810

Einige neue Versuche über Herzbewegung.

Experimental ventricular fibrillation.

1889 CE

#7996

Electrical stimulation of the heart in man.

MacWilliams described experiments in which application of an electrical impulse to the human heart in asystole caused a ventricular contraction, and that a heart rhythm of 60–70 beats per minute could be evoked …

1912 CE

#2840

Electro-cardiography and its importance in the clinical examination of heart affections.

1934 CE

#2864

Electrocardiograms that represent the potential variations of a single electrode.

Unipolar leads. With F. D. Johnston, A. G. MacLeod, and P. S. Barker.

1947 CE

#2876

Electrokymograph for recording heart motion, improved type.

With B. R. Boone and W. E. Chamberlain.

1936 CE

#2865.1

Elektrographische Diagnostik der Herzmuskelerkrankungen.

Introduction of the vectorcardiogram.

1909 CE

#11680

Elektrokardiogramme.

This 37-page pamphlet was the earliest collection of information regarding electrocardiography. It contained "only single lead electrocardiograms, limited to mitral stenosis and hypertrophy of the right and left venti…

1904 CE

#3132.1

Elliptical human red cell corpuscles.

Hereditary elliptocytosis.

1671 CE–1672 CE

#2726.1

Embryo monstro affinis Parisiis dissectus.

First known description of the “tetralogy of Fallot” (see No. 2792). Reprinted in his Opera philosophica, ed. W. Maar, Vol. 2, Copenhagen, V. Tryde, 1910, pp. 49-53. For translation see Proc. Mayo Clin., 1…

1910 CE

#2836

Endocarditis lenta. Zugleich ein Beitrag zur Artunterscheidung der pathogenen Streptokokken.

First to isolate Strep viridans in cases of bacterial endocarditis, Schottmüller named the condition Endocarditis lenta.

1985 CE

#10785

Enzymatic amplication of B-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia.

Polymerase chain reaction first published. With Randall K. Saiki, Stephen Scharf, Fred Faloona et al. Order of authorship in the original paper was Saiki, Scharf, Faloona, Mullis.... In 1993 the Nobel Prize in Chemist…

1958 CE

#1931.6

Enzymatic O-methylation of epinephrine and other catechols.

The authors discovered the enzyme "COMT" or cathecol-O-methyltransferase, and determined that it was crucial in the methylation and inactivation of adrenergic and other catecholamine type neurotransmitters. (Thanks to…

1735 CE

#3051

Epistolica dissertatio altera pro spicilegio observationum de morbo maculoso haemorrhagico et noxiis nonnulis mytulis perscripta.

Behrens gave the name “morbus maculosus haemorrhagicus” to the disease purpura haemorrhagica. His paper is reprinted in Werlhof’s Opera medica, Hannover, 1775, 2,615-36.

1931 CE

#2990

Erfolgreiche operative Beseitigung eines Aneurysma der rechten Herzkammer.

First successful surgical intervention in cardiac aneurysm.

1924 CE

#907.1

Ergebniss einer biostatischen zusammenfassenden Betrachtung über die erblichen Blutstrukturen des Menschen.

Bernstein, a mathematician, determined the correct blood group inheritance pattern of multiple alleles at one locus through statistical analysis.