Facets

1896 CE

#4125

Sopra una dermatosi telangettode non ancora descritta “Purpura annularis” “Telangectasia follicularis annulata” studio clinico.

Purpuraannularis telangiectodes (Majocchi) first described.

1878 CE

#3768

Specimens illustrative of the pathology of lymphadenoma and leucocythemia

Greenfield also drew attention to the giant cells in lymphadenoma, which later became known as “Dorothy Reed’s giant cells” (see No. 3780).

1897 CE

#11272

Sporadic cretinism in America.

In 1893 Osler was among the first American physicians to use thyroid extract to treat myxedema or cretinism. He made a special study of the disease, corresponding with physicians across America to try to determine its…

1920 CE

#2645

Squamous-cell epithelioma of the lip. A study of five hundred and thirty-seven cases.

Broders’s classification of tumors, an index of malignancy.

1965 CE–1977 CE

#2660.21

Statistical studies in the aetiology of malignant neoplasms. 5 vols.

Acta path. microbiol. scand., Suppl. 174 (Pts. 1-2), 209, 247, 261.

1881 CE–1894 CE

#534.67

Storia della teratologia. 8 vols. (Tomo 1-3, 5-7 called pt. 1; t. 4 and 8 called pt. 2, Note ed osservazioni.)

The most extensive history and bibliography of teratology ever published, even though the section on malformations of single organs and parts was never completed. Contains excerpts and detailed abstracts of innumerabl…

1793 CE

#11576

Storia di un monocolo con alcune riflessioni.

A rather elegantly produced and illustrated medical monograph on a cyclops, with plates printed in sepia. Engraved headpieces allude to monsters from classical mythology Digital facsimile from Google Books at this link.

1971 CE

#14231

Structure of the porcine LH-and FSH-releasing hormone. II. Confirmation of the proposed structure by conventional sequential analyses.

Publication in May 1971: Working with pig preparations, the authors reinvestigated the peptide that they had previously isolated, which acted as an LH-FSH releasing hormone. They performed an Edman-dansyl degradation …

1921 CE

#2601.1

Studien über die Ueberempfindlichkeit.

Prausnitz–Küstner reaction. These workers demonstrated antibodies in the blood of persons suffering from atopic allergic diseases. They produced local passive sensitization by intracutaneous injection of se…

1963 CE–1964 CE

#534.9

Studien zur Historik der Teratologie.

1932 CE

#2605

Studies in anaphylaxis.

Detection of the release of histamines into the circulation during anaphylactic reaction. Thereafter histamine was identified as Lewis’s “H-substance.”

1948 CE

#3908

Studies in growth. I. Interrelationship between pituitary growth factor and growth-promoting androgens in acromegaly and gigantism. II. Quantitative evaluation of bone and soft tissue growth in acromegaly and gigantism.

L. W. Kinsell, G. D. Michaels, C. H. Li, and W. E. Larsen showed that there is an increase in growth hormone in plasma in acromegaly.

1953 CE

#4672.2

Studies in human subjects on active immunization against poliomyelitis. 1. A preliminary report of experiments in progress.

Killed-virus vaccine. With four co-authors.

1926 CE

#14313

Studies in intracranial physiology & surgery. The third circulation. The hypophysis. The gliomas. The Cameron Prize Lectures delivered at the University of Edinburgh October 19, 20, 22, 1925.

This series of three lectures was an analytical review by Cushing of the three main categories of scientific work that he had accomplished during the previous 25 years. Remarkably, Cushing completed this review and de…

1960 CE

#5449.4

Studies on an attenuated measles-virus vaccine. I. Development and preparation of the vaccine: technics for assay of effects of vaccination.

Live virus vaccine. With M. V. Milovanovič, and A. Holloway.

1939 CE

#3098

Studies on leukemia with the aid of radioactive phosphorus.

Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley Nationa…

1956 CE

#2578.20

Studies on organ specificity. IV. Production of rabbit thyroid antibodies in the rabbit.

Autoimmune thyroiditis

1941 CE

#4276

Studies on prostatic cancer. I. The effect of castration, of estrogen, and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate.

In 1966 Huggins was awarded the Nobel Prize for Physiology or Medicine for discovering in 1941 "for his discoveries concerning hormonal treatment of prostatic cancer."

1952 CE

#11103

Studies on the cultivation of poliomyelitis viruses in tissue culture.

Order of authorship in the original publication: Weller, Enders, Robbins. In this paper the authors describe their improved method for culturing poliomyelitis viruses in "normal kidney tissue." Followed by Robbins, We…

1909 CE

#1132

Studies on thyroid. I. The relation of iodine to the physiological activity of thyroid preparations.

1789 CE

#3809

Su i gozzi e sulla stupidità che in alcuni paesi gli accompagna tentativi

Hirsch considered this the first important work on cretinism and goitre. See also Malacarne’s Lettre, in J. P. Frank: Delectus opusculorum medicorum, 1789, 6, 241-58. Digital facsimile of Malacarne's pamphlet fr…

1933 CE

#3205

Successful removal of entire lung for carcinoma of the bronchus.

First reported case: April 5, 1933.

1896 CE

#3857

Sugli effeti dell’ estirpazione delle ghiandole paratiroidee.

Demonstration that tetany follows removal of the parathyroids. A French translation of the paper is in Arch. ital. Biol., 1896, 25, 459-64.

1892 CE

#1157

Sulla distruzione della ghiandola pituitaria.

Vassale and Sacchi showed water and mineral metabolism to be affected by hypophysectomy.

1895 CE

#5170

Sulla preparazione del siero anti-carbonchioso.

Specific anti-anthrax serum. German translation in Zbl. Bakt., 1895, 1 Abt., 18, 744-45.

1878 CE

#4074

Summer prurigo, prurigo aestivalis, seu prurigo adolescentium, seu acne-prurigo.

Hutchinson’s summer prurigo.

1932 CE

#2655

Superior pulmonary sulcus tumor. Tumor characterized by pain. Horner’s syndrome, destruction of bone and atrophy of hand muscles.

“Pancoast’s tumor.”

2005 CE

#13622

Suppression of RNA recognition by toll-like receptors: The impact of nucleoside modification and the evolutionary origin of RNA.

Karikó and Weissman discovered the nucleoside modifications that suppress the immungenicity of RNA, leading to their patents for the application of non-immunogenic, nucleoside-modified RNA (modRNA). This techno…

1929 CE

#3873

Suprarenal cortical extracts in suprarenal insufficiency (Addison’s disease).

Rogoff and Stewart were the first to use adrenal cortical extract (“inter-renalin”) in the treatment of adrenal insufficiency. See also No. 1148.

1886 CE

#3884

Sur deux cas d’acromégalie. Hypertrophie singulière non congénitale des extrémités supérieures, inférieures et céphalique.

In this, the first complete clinical description of the condition, Marie suggested the name “acromegaly”. The paper excited much interest and was translated into English and published by the New Sydenham S…

1898 CE

#2551

Sur l’agglutination et la dissolution des globules rouges par le sérum d’animaux injectés de sang défibriné.

Bordet’s important work on immune hemolysis turned the attention of many investigators towards the subject. English translation in J. Bordet et al., Studies in immunity, New York, 1909, p. 134.

1880 CE

#5169

Sur l’étiologie du charbon.

First use of attenuated bacteria for therapeutic purposes. See also the same journal, 1881, 92, 1378-83.

1901 CE

#2553

Sur l’existence de substances sensibilisatrices dans la plupart des sérums antimicrobiens.

The Bordet–Gengou complement-fixation reaction is the basis of many tests for infection, notably the Wassermann test for syphilis, and reactions for gonococcus infection, glanders, hydatid disease. English trans…

1835 CE

#1698.1

Sur l’homme et le développement des facultés, ou essai de physique sociale. 2 vols.

Quetelet’s statistical researches on the development of the physical and intellectual qualities of man, and an exposition of his concept of the “average man”, which became the by-word of quantitative…

1898 CE

#2334

Sur l’obtention de cultures et d’émulsions homogènes du bacille de la tuberculose humaine en milieu liquide et “sur une variété mobile de ce bacille”.

Sero-agglutination for the diagnosis of tubercle bacillus.

1857 CE–1858 CE

#4046

Sur la coloration partielle en noir ou en bleu de la peau chez les femmes.

Chromidrosis first described.

1895 CE

#2548

Sur la destruction extracellulaire des bactéries dans l’organisme.

See No. 2538

1883 CE

#3830

Sur la nature et sur quelques-uns des symptomes de la maladie de Basedow.

The fourth cardinal sign in exophthalmic goitre – tremor – was first mentioned by Pierre Marie.

1829 CE

#5291

Sur la pyrophlyctide endémique, ou pustule d’Aleppo.

Important description of “Aleppo boil”, furunculosis orientalis.

1927 CE

#2346

Sur la vaccination préventive des enfants nouveau-nés contre la tuberculose par le B.C.G.

1933 CE

#5151

Sur la valeur et la durée de l’immunité conférée par l’anatoxine tétanique dans la vaccination de l’homme contre le tétanos.

Tetanus toxoid first employed in the immunization of humans.

1891 CE

#1130

Sur les fonctions du corps thyroïde.

Gley re-discovered the parathyroids and later came across Sandström’s description (see No. 1127). Gley seems to have been the first to understand their real significance; his work showed the necessity of th…

1880 CE

#2537

Sur les maladies virulentes, et en particulier sur la maladie appelée vulgairement choléra des poules.

This paper marked the beginning of Pasteur’s work on the attenuation of the infective organism. Noting that fowls inoculated with an attenuated form of the chicken cholera bacterium acquired immunity, he develop…

1896 CE

#2001

Sur les radiations émises par phosphorescence.

The discovery of radioactivity – research stimulated by Roentgen’s discovery of x rays. In 1903 Becquerel received half of the Nobel Prize in Physics 1903 "in recognition of the extraordinary services he h…

1842 CE

#4034

Sur une espèce de mentagre contagieuse résultant du développement d’un nouveau cryptogame dans la racine des poils de la barbe de l’homme.

First accurate description of Trichophyton mentagrophytes, the fungus responsible for sycosis barbae. English translation of this and Gruby’s other five papers read to l’Académie des Sciences in Zak…

1929 CE

#4397

Sur une forme de dystrophie osseuse familiale.

“Morquio’s disease”, eccentro-osteochondrodysplasia.

1889 CE

#4101

Sur une nouvelle forme de dermatite pustuleuse chronique en foyer à progression excentrique.

Pyodermite végétante. Hallopeau described a suppurative form of Neumann’s pemphigus vegetans.

1898 CE

#2003

Sur une substance nouvelle radio-active, contenue dans la pechblende.

The Curies, studying the radioactivity of minerals containing uranium and thorium, isolated from pitchblend a substance which they called radium and which they showed to possess an astonishing degree of radioactivity.…

1960 CE

#7878

Surgical diseases of the pancreas.

The first comprehensive textbook on pancreatic disease.

1818 CE–1819 CE

#2941

Surgical essays. 2 vols.

Cooper, the pupil and great interpreter of Hunter, was the most popular surgeon in London during the Regency. In 1802 he gained the Copley Medal of the Royal Society. Travers was surgeon to St. Thomas’s Hospital…