Facets

1949 CE

#2924.1

Le traitement de l’artérite oblitérante parla greffe veineuse.

Kunlin, an associate of R. Leriche, first reported the use of a bypass venous graft for femoropopliteal occlusive arterial disease.

1855 CE–1856 CE

#615

Leçons de physiologie expérimentale appliquée à la médecine. 2 vols.

Claude Bernard made strenuous efforts to introduce experimental methods into physiology. The above includes his classic work on the function of the liver, pancreas, and gastric glands. Vol. 1, p. 126: Catheterization …

1846 CE

#2902

Lectures illustrative of various subjects in pathology and surgery.

Page 361 contains the first description of intermittent claudication in man. This was first reported (in the horse) by “Boullay” [?J. Bouley] in Arch. gén. Méd.,1831, 27, 425. P. 186: Brodie'…

1897 CE

#11651

Lectures on angina pectoris and allied states.

"This monograph, based on seven lectures Osler delivered at Johns Hopkins, is his longest publication dealing with heart disease. He discusses the history of the recognition of angina, the pathophysiology of coronary …

1846 CE

#2755.1

Lectures on subjects connected with clinical medicine, comprising disease of the heart. Second edition, 2 vols.

Includes (vol. 2, pp. 373-79) a classic description of coronary thrombosis, although not using the term. The patient was Thomas Arnold, the educationist, and the report was signed by Joseph Hodgson and by S. Bucknill,…

1839 CE

#2585

Lectures on the blood, and on the changes which it undergoes during disease: Delivered at the College of France in 1837-8.

Pp. 244-49: Magendie showed that secondary or subsequent injections of egg/albumin caused death in rabbits who had tolerated an initial injection. This was the first experiment in anaphylaxis, though Jenner in 1798 ha…

1911 CE

#2837

Les arythmies.

1931 CE

#2920

Les dérivés du thorium dans l’artériographie des membres.

Thorotrast first used in arteriography.

1974 CE

#2028.43

Les origines de la transfusion sanguine.

Reprinted from Clio Medica, Vol. 9, 1974.

1945 CE

#11687

Les tumeurs et les polypes du coeur: Étude anatomo-clinique.

A classical monograph on heart tumors with 1298 references on these relatively rare tumors.

1667 CE

#2013

Lettre … touchant deux expériences de la transfusion faites sur des hommes.

The first transfusion of blood into a human was performed by Denis on June 15, 1667; he transfused lamb’s blood into a youth. For a partial translation, see Geoffrey Keynes’s Blood transfusion (Bristol, 19…

1768 CE

#2886

Lettre de M. Rougnon à M. Lorry, touchant les causes de la mort de feu Monsieur Charles, ancien capitaine de cavalerie, arrivé à Besançon le 23 février 1768.

Osler, Allbutt, and several other authorities believe this to be the description of an authentic case of angina, thus preceding Heberden’s classic account. Other eminent authorities consider the patient to have …

1946 CE

#3106

Leukaemia treated with urethane compared with deep x-ray therapy.

Urethane in treatment of leukemia. With A. Haddow, I. Ap Thomas, and J. M. Watkinson.

1957 CE

#2578.23

Leukocyte agglutinins in human sera. Correlations between blood transfusions and their development.

Leucocyte typing.

1519 CE

#3048

Liber theoricae nec non practicae Alsaharavii.

This is the first printing of the medical and therapeutic section of Abul Qasim’s medical encyclopedia or al-Tasrif. It contains what is probably the earliest description of hemophilia (fol. 145). Digital facsim…

1907 CE

#3025.3

Ligation of the ductus arteriosus.

Munro was first to suggest the feasibility of ligation of a patent ductus arteriosus.

2001 CE

#7191

Machines in our hearts: The cardiac pacemaker, the implantable defibrillator, and American health care.

1889 CE

#2796

Maladies du coeur et des vaisseaux.

In his important monograph on disorders of the cardiovascular system, Huchard was apparently the first to use the designation “Stokes–Adams disease”.

1966 CE

#3155.4

Man’s haemoglobins: including the haemoglobinopathies and their investigation.

Explains the current distribution of sickling throughout the world.

2019 CE

#11482

Mapping human microbiome drug metabolism by gut bacteria and their genes.

Order of authorship in the original publication: Zimmermann, Simmerman-Kogadeeva, Wegmann....The authors looked at 271 drugs and 68 different species from the main taxonomic microbiome groups. Of the 271 drugs, 176 un…

1980 CE

#11689

Marey and cardiology: physiologist and pioneer of technology (1830-1904).

1992 CE

#11555

Mechanisierung des Herzen: Harvey und Descartes- Der Vitale und der mechanische Aspekt des Kreislaufs.

Translated into English by Marjorie Grene as The mechanization of the heart: Harvey and Descartes. Rochester, NY: University of Rochester Press, 2001.

1927 CE

#5630.2

Mechanism and treatment of experimental shock. I. Shock following hemorrhage.

First of a series of papers in the Archives. See also No. 5630.3.

1950 CE

#2881

Mechanism of the auricular arrythmias.

With E. Corday, I. C. Brill, A. L. Seller, R. W. Oblath, W. A. Flieg, and H. E. Kruger.

1554 CE

#2271

Medicina. 3 pts.

The first systematic treatise on pathology, which also introduced the names for the sciences of pathology and physiology. In the second part, entitled “Pathologia”, Fernel provided the first systematic ess…

1554 CE

#3109

Medicinalium epistolarum miscellanea.

Epistle xxi, pp. 74-77, contains the first definite description of chlorosis. “De morbo virgineo”. English translation in No. 2241.

1921 CE

#1756

Medicolegal application of human blood grouping.

An important series of papers on blood-grouping and the jurisprudence of paternity. Ottenberg performed the first matched-blood transfusion.

1929 CE

#2857

Medionecrosis aortae idiopathica (cystica).

Classic description of aortic medionecrosis.

1936 CE

#3148.1

Mediterranean disease – thalassemia (erythroblastic anemia of Cooley); associated pigment abnormalities simulating hemochromatosis.

Whipple and Bradford contributed a classic paper on the pathology of thalassemia, a name introduced by them.

1552 CE

#7807

Meletius, De natura structuraque hominis opus. Polemonis Atheniensis, Naturae signorum interpretationis. Hippocratis, De hominis structura. Diocles, De tuenda valetudine epistola. Melampus, De nevis corporis tractatus. Omnia haec non prius edita. Nicolao Petreio Corcyraeo interprete.

This collection of Late Antique and Byzantine medicine edited by Nicolas Petreius begins with a Byzantine treatise on anatomy, probably written in the eighth century by Meletius, a Christian monk and physician from Ph…

1817 CE

#2744

Mémoire sur cette question de l’asthme des vieillards: est-il une affection nerveuse?

Rostan gave an early description of cardiac (“Rostan’s”) asthma.

1844 CE

#1859

Mémoire sur l’alcool amylique.

Discovery of amyl nitrite.

1822 CE

#6171

Mémoire sur l’auscultation appliquée à l’étude de la grossesse.

Although not the first to record the auscultation of the fetal heart sound, Le Jumeau (Kergaradec), a pupil of Laennec, brought the importance of this diagnostic procedure to the notice of the medical profession. Laen…

1845 CE

#1860

Mémoire sur la digitale pourprée.

Isolation of an active principle in digitalis, amorphous digitalin, more potent than the plant itself.

1831 CE

#2977

Mémoire sur la piqûre ou l’acupuncture des artères dans le traitement des anévrismes.

First attempt at operative treatment of aneurysm.

1859 CE

#12874

Mémoire sur le sang quand il est fluide, pendant qu’il se coagule et lorsqu’il est coagulé.

The first attempt to isolate and describe fibrinogen, the blood protein essential for clotting. “Prosper-Sylvain Denis, in his Mémoire sur le sang (1859), was the first to recognize that plasma contained …

1843 CE

#2754

Mémoire sur les signes stethoscopiques du rétrécissement de l’orifice auriculo-ventriculaire gauches du coeur.

First description of the presystolic murmur in mitral stenosis. Partial English translation in No. 2241.

1684 CE

#861

Memoirs for the natural history of humane blood, especially the spirit of that liquor.

The first analysis of blood, Boyle’s Memoirs may be considered the first scientific study in physiological chemistry, exhibiting methods which have become universally adopted. This is Boyle’s most importan…

1882 CE

#882

Mésure du volume de sang contenu dans l’organisme d’un mammifére vivant.

A method of determining blood volume with carbon monoxide.

1879 CE–1880 CE

#880

Methodologische Beiträge zur Physiologie und Pathologie der verschiedenen Formender Leukocyten.

Foundation of the differential blood count technique.

1628 CE

#2011

Methodus facile parandi iucunda tuta et nova medicamenta & eius applicatio aduersus chimicos.

Page 170 includes the first definite description of a blood transfusion, notably published in the same year as Harvey's discovery of the circulation of the blood in De motu cordis. Digital facsimile from Google Books …

1674 CE

#860

Microscopical observations concerning blood, milk, bones, the brain, spittle, and cuticula, etc.

First really accurate description of the red blood corpuscles, which Swammerdam had noted in 1658.

1961 CE

#3047.16

Mitral replacement: The shielded ball valve prothesis.

On September 21, 1960, Starr successfully inserted a “ball-in-cage” prosthetic valve (the Starr-Edwards heart valve) into a patient’s mitral valve, which was severely diseased as a result of rheumati…

1968 CE

#6916

Molecular pathology of human haemoglobin.

Perutz opened up "the field of 'molecular pathology,' relating a structural abnormality to a disease" (Aaron Klug, "Max Perutz 1914-2002," Science 295 ([2002] 2383). Specifically Perutz showed that hemoglobin molecule…

1919 CE

#906

Morphologische Hämatologie. Vol. 1.

1897 CE

#2986

Multiple aneurysms of the pulmonary artery.

Churton was the first to recognize this condition at necropsy.

1869 CE

#2767

Mycosis endocardii.

Winge first suggested that endocarditis was due to microbial infection. A translation of part of his paper is in Major, Classic descriptions of disease, 3rd ed., 1945, p. 472.

1953 CE

#3108.4

Myleran in chronic myeloid leukaemia: chemical constitution and biological action.

Introduction of myleran (busulphan). For results, see pp. 208-13.

1974 CE

#12718

Myocardial infarction due to coronary thromboarteritis following acute febrile mucocutaneous lymph node syndrome (MLNS) in an infant.

The authors reported the case of a 6 month old baby who died from a myocardiac infarction after "recovering" from Kawasaki disease. Autopsy showed that the baby died from classical coronary artery thrombosis accompani…

1990 CE

#12334

Mysterious heparin: The key to open heart surgery.