PERUTZ, Max Ferdinand (1914 – 2002)
1914 – 2002
5 entries in the GMN corpus.
Image source Associated Press · [1] · Public domain
1954 CE
#14223
The structure of haemoglobin - IV. Sign determination by the isomorphous replacement method.
The first demonstration of isomorphous replacement in protein crystallography. This was a key step in determination of the structure of large biological molecules. Harittai, "On the origins of isomorphous replacement …
1960 CE
#14283
Structure of haemoglobin: A three-dimensional Fourier synthesis at 5.5-A. resolution, obtained by X-ray analysis.
Solution of the structure of hemoglobin, a protein with 10,000 atoms. This was the culmination of 30 years of research by Perutz. Order of authorship in the original paper: Perutz, Rossmann, Culis, Muirhead, Will, Nor…
1968 CE
#6916
Molecular pathology of human haemoglobin.
Perutz opened up "the field of 'molecular pathology,' relating a structural abnormality to a disease" (Aaron Klug, "Max Perutz 1914-2002," Science 295 ([2002] 2383). Specifically Perutz showed that hemoglobin molecule…
1968 CE
#6913
Three-dimensional Fourier synthesis of horse oxyhaemoglobin at 2.8Å resolution: The atomic model.
Thirty years after beginning his research on hemoglobin Perutz solved the Fourier synthesis of hemoglobin at 2.8Å (high resolution) and built an atomic model of the molecule. With Hilary Muirhead, J. M. Cox & L.…
1997 CE
#11069
Science is not a quiet life: Unravelling the atomic mechanism of haemoglobin.
Reprints landmark papers with commentary by Perutz.