Facets

2001 CE

#12890

Linus Pauling: Selected scientific papers. Vol. 1: Physical sciences. Vol. 2: Biomolecular sciences. Edited by Barclay Kamb, Linda Pauling Kamb, Peter Jeffress Pauling, Alexander Kamb, Linus Pauling, Jr.

1861 CE

#688

Liquid diffusion applied to analysis.

Graham’s method of separating animal and other fluids by dialysis introduced the distinction between colloidal and crystalloid substances.

1885 CE

#706

Lois d’équilibre chimique dans l’état dilué, gazeux ou dissous.

Van’t Hoff stated that osmotic pressure is proportional to the concentration if the temperature remains invariable, and proportional to the absolute temperature if the concentration remains invariable. In 1901 V…

2018 CE

#13566

Luminous creatures: The history and science of light production in living organisms.

1897 CE

#3775

Lymphosarkom (Lymphosarkomatose, Pseudoleukämie, Myelom, Chlorom).

“Paltauf-Sternberg disease” (see also No. 3776). On the European Continent the name “Hodgkin-Paltauf-Sternberg disease” is in use.

1972 CE

#1588.11

Machina carnis: the biochemistry of muscular contraction in its historical development.

A definitive history of the development of knowledge on muscle biochemistry; valuable bibliography.

2005 CE

#11193

Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: A double blind randomized placebo-controlled trial.

Order of authorship in the original paper: Taylor, Makunde, McGarry.... The authors treated infection by the parasitic worm Wuchereria bancrofti, cause of elephantiasis (lymphatic filariasis), by killing the Wolbachia…

1983 CE

#14140

Mammalian beta-adrenergic receptors. Structural differences in beta 1 and beta 2 subtypes revealed by peptide maps.

Lefkowitz and colleagues showed that there are two different types of beta receptors, distinguishing them as Beta-1 and Beta-2. They noticed that each has specific pharmacological characteristics. Order of authorship …

1918 CE

#9597

Manual of medical research laboratory.

Digital facsimile from Google Books at this link.

1785 CE

#924

Mémoire sur l’affinité du principe oxygine avec les différentes substances auxquelles il est susceptible de s’unir.

1784 CE

#592

Mémoire sur la chaleur.

These workers invented an ice calorimeter, with it measured the respiratory quotient of a pig, and demonstrated the analogy between respiration and combustion.

1791 CE

#926

Mémoire sur la combinaison de l’oxigéne avec le carbone et l’hydrogéne du sang, sur la dissolution de l’oxigéne dans le sang, et sur la maniére dont le calorique se dégage.

Hassenfratz, a pupil of Lagrange, maintained that the oxidation of carbon and hydrogen took place in the blood, and not in the lungs as taught by others.

1820 CE

#668.3

Mémoire sur la conversion de matiéres animales en nouvelles substances par le moyen de l’acide sulfurique.

Isolation of glycine and leucine.

1838 CE

#675

Mémoire sur la fermentation vineuse.

The earliest demonstration of the true nature of yeast was made by Cagniard-Latour in 1836. All his work on the subject is summed up in this paper. Digital facsimile from Google Books at this link.

1784 CE

#923

Mémoire sur la formation de l’acide, nommé air fixe ou acide crayeux, et que je désignerai désormais sous le nom d’acid du charbon.

1778 CE

#922

Mémoire sur la nature du principe qui se combine avec les métaux pendantleur calcination, et qui en augmente le poids.

Although Priestley isolated oxygen, it was Lavoisier who discovered its real significance. He showed the true nature of the interchange of gases in the lungs and exploded Stahl’s phlogiston theory. Lavoisier was…

1854 CE

#2124

Mémoire sur les effets de la compression de l’air.

An early paper on “caisson sickness”.

1684 CE

#861

Memoirs for the natural history of humane blood, especially the spirit of that liquor.

The first analysis of blood, Boyle’s Memoirs may be considered the first scientific study in physiological chemistry, exhibiting methods which have become universally adopted. This is Boyle’s most importan…

1889 CE

#9525

Merck's index of fine chemicals and drugs for the materia medica and the arts: Comprising a summary of whatever chemical products are to-day adjudged as being useful in either medicine or technology, with average values and synonyms affixed; a guide for the physician, apothecary, chemist, and dealer.

First edition of the Merck Manual. Digital facsimile from the Internet Archive at this link.

1941 CE

#6898

Metabolic generation and utilization of phosphate bond energy.

In this paper about group potential and the transfer of acetyl and phosphoryl groups Lipmann proposed that acetyl phosphate acted as an acetyl door in the biosynthesis of essential metabolites and that ATP functioned …

1837 CE

#1105

Microscopische Beobachtungen über die sichtbare Fortbewegung der Lymphkörnchen in den Lymphgefässen der Froschlarven.

1997 CE

#8749

Moving questions: A history of membrane transport and bioenergetics.

"This book describes half a century of progress in two mainstream areas of biological research: membrane transport, initially a focus of physiologists, and oxidative phosphorylation, initially a focus of biochemists. …

1913 CE

#657

Muscular work. A metabolic study.

1978 CE

#13986

Mutagenesis at a specific position in a DNA sequence.

Smith and Hutchison introduced site-directed mutagenesis, or oligonucleotide-directed mutagenesis, into molecular biology, resolving the problem of how to determine the effect of a single mutant gene with efficiency. …

1895 CE

#1888

Neue Synthese der Harnsäure und ihrer Methylderivate.

1832 CE

#672

Neues eigenthümliches stickstoffhaltiges Princip, in Muskelfleisch gefunden.

Isolation of creatine from muscle.

1820 CE–1821 CE

#11411

Neueste phytochemische Entdeckungen zur Begründung einer wissenschaftlichen Phytochemie. 2 vols.

On pp. 144-146 of vol. 1 Runge reported the isolation of relatively pure caffeine for the first time. He called it "Kaffebase." Digital facsimile from Google Books at this link. In 1821 the French chemists Pierre-Jose…

1660 CE

#914

New experiments physico-mechanical touching the spring of the air.

Boyle showed the effects of the elasticity, compressibility, and weight of air. He investigated the function of air in respiration, combustion, and conveyance of sound. Most significantly Boyle demonstrated that air i…

1863 CE

#5344.3

Note sur une tumeur des bourses contenant un liquide laiteux (galactocèle de Vidal) et renfermant de petits êtres vermiformes que l’on peut considérer comme les helminthes hèmatoïdes à l’étatd’embryon.

Description of the embryonic stage of Wuchereria bancrofti in hydrocele fluid.

1906 CE

#730.1

Note upon the presence of amino-acids in the blood and lymph as determined by the ß naphthalinsulphochloride reaction.

Demonstration of the presence of amino-acids in the blood.

1868 CE

#5344.6

Noticiar preliminar sobre vermes de uma especie ainda nao descripta, encontrados na urina de doentes de hematuria intertropical no Brazil.

In 1866 Wucherer saw the embryo form of the filaria worm. Later the name Wuchereria bancrofti was applied to it. English translation in Kean (No. 2268.1).

1844 CE

#679

Notiz über eine neue Reaction auf Galle und Zucker.

Pettenkofer’s test for bile. Previously there had been no means of recognizing the presence of the bile salts.

1827 CE

#670

Nouvelles observations sur l’endosmose et l’exosmose.

The process by which water passes through a membrane from a solution on the one side to another solution on the other side has been known, since the classic work of Dutrochet, as “endosmosis” or “exo…

1653 CE

#1098

Nova exercitatio anatomica, exhibens ductus hepaticos aquosos, et vasa glandularum serosa.

Rudbeck claimed to have discovered the intestinal lymphatics and their connexion with the thoracic duct in 1651, a claim disputed as to priority by Bartholin (Nos. 1096-97). This book was reproduced in facsimile in 19…

1673 CE

#12972

Nova medicina spirituum: Curiosa scientia & doctrina, unanimiter hucusque neglecta, & à nemine meritò exculta, medicis tamen & physicis utilissima. In quâ Primo Spirituum naturalis constitutio, vita, sanitas temperamenta, ingenia, calidum innatum, phantasiae vires, ideae, astrorum influentiae, μετεμψύχωσις, rerum magnetissimi, sympatiae & antipatiae, qualitates hactenus occultae, aliaq; caeteroquin abstrusa & paradoxa; Dehinc spirituum praeternaturalis seu morbosa Dispositio, causae, curationes per naturam, per diaetam, per arcana majora, palingenesiam, magnetissimum seu sympatheismum, transplantationes, amuleta, ingenuè & dilucidè demonstrantur.

”A very curious work, attributing the causes of many diseases to spirits and basing their cure on this theory. There is a great deal on insanity. The methods of treatment are partly chemical, partly magnetical, …

1772 CE

#920

Observations on the different kinds of air.

The isolation of oxygen was first achieved by Priestley. He also demonstrated that plants immersed in water give off oxygen and that this gas is essential for animal life.

1773 CE

#667

Observations sur l’urine humaine.

Discovery of urea, independently of Boerhaave. Rouelle isolated urea as the alcohol-soluble substance from urine. He was the first to present proof of the high nitrogen content of urea.

1921 CE

#745

On an autoxidisable constituent of the cell.

Isolation of glutathione.

1906 CE

#731

On carbohydrate metabolism.

1810 CE

#668.1

On cystic oxide, a new species of urinary calculus.

Cystine, the first amino-acid to be isolated, was prepared by Wollaston from a urinary calculus. This was also the first report of cystinuria.

1854 CE

#686

On osmotic force.

Investigation of osmotic force; provided important information for the physiologists.

1832 CE

#3762

On some morbid appearances of the absorbent glands and spleen.

First full description of lymphadenoma, which Wilks in 1865 referred to as “Hodgkin’s disease”. This is more typically designated as Hodgkin's lymphoma. In 1666 Malpighi had vaguely outlined the cond…

1844 CE

#12695

On superstitions connected with the history and practice of medicine and surgery.

Digital facsimile from the Hathi Trust at this link.

1896 CE

#647

On the absorption of fluids from the connective tissue spaces.

Starling discovered the functional significance of the serum proteins.

1868 CE–1869 CE

#1867

On the connection between chemical constitution and physiological action.

Brown and Fraser were the first to investigate the relationship between the chemical constitution of substances and their action upon the body. "Although Crum Brown apparently never contemplated the practice of medici…

1892 CE

#718

On the estimation of uric acid in the urine: a new process by means of saturation with ammonium chloride.

Hopkins’s method of estimating uric acid in urine.

1857 CE

#687

On the immediate principles of human excrements in the healthy state.

First important publication on coprosterol as a product of excretion.

1824 CE

#987

On the nature of the acid and saline matters usually existing in the stomachs of animals.

Proof that the gastric juice contains free hydrochloric acid.

1871 CE

#626

On the physiological effects of severe and protracted muscular exercise; with special reference to the influence of exercise upon the excretion of nitrogen.

Flint made investigations on the nitrogen output of a long-distance walker, before, during, and after the latter’s attempt to walk 400 miles in five days. The useful data in this paper are often referred to in d…

1905 CE

#1893.2

On the reaction of cells and of nerve-endings to certain poisons, chiefly as regards the reaction of striated muscle to nicotine and to curari.

Langley introduced the concept of a receptor substance present in the biological object with which a drug has to interact in order to exert its biological effect. Digital facsimile from PubMedCentral at this link.