Facets

1679 CE

#974.1

Cicutae aquaticae historia et noxae.

This is primarily a work on the poisonous water hemlock, its dangerous effects, its medicinal uses, and antidotes to counter the poison. However, it also contains the first description of the tiny glands in the mucosa…

1887 CE

#3488

Circular suture of the intestines; an experimental study.

Halsted set down some of the fundamental rules regarding intestinal anastomosis.

1856 CE

#5183.2

Clinica médica. Abcesos del higado.

Jimenez gave a classic account of liver abscess in amoebiasis.

1868 CE

#3622

Clinical lectures on diseases of the liver.

1961 CE

#11979

Combined electron and light microscopy in Whipple's disease. Demonstration of "bacillary bodies" in the intestine.

Order of authorship in the original publication: Yardley, Hendrix. The authors made the first observations of previously uncultured, unseen and unidentified bacilli associated with Whipple's disease, suggesting that i…

1859 CE

#3459

Commentatio de fistulis ventriculi externis et chirurgica earum sanatione.

First operation for gastric fistula.

1888 CE

#3630

Contribution à l’étude clinique et anatomo-pathologique du cancer primitif du pancréas.

“Bard-Pic syndrome” first described.

1874 CE

#3623

Contribution à l’étude de l’hépatite interstitielle chronique avec hypertrophie (sclérose ou cirrhose hypertrophique du foie).

Classic description of chronic interstitial hepatitis.

1884 CE

#3946

Contribution à l’étude du pancreas du lapin. Lésions provoquées par la ligature du canal de Wirsung.

Arnozan and Vaillard showed that blockage of the pancreatic ducts caused atrophy of the pancreas but not diabetes.

1899 CE

#3639.1

Contribution to the surgery of the bile passages, especially of the common bile-duct.

“Among Halsted’s many outstanding surgical accomplishments those related to surgery of the biliary tract are lesser known. However, he is commonly credited with performing the first successful operation fo…

1925 CE

#1037

Contributions to the physiology of gastric secretion. The proof of a humoral mechanism. A new procedure for the study of gastric physiology.

1912 CE–1913 CE

#1030

Contributions to the physiology of the stomach.

Carlson recorded stomach movements by means of a balloon inserted through a gastric fistula. Much of his important work on gastric physiology was summed up in his book published in 1916. See No. 1033.

1930 CE

#1038.1

Crystalline pepsin.

Crystallization of pepsin and its identity as a protein. In 1946 Northrop shared half of the Nobel Prize in Chemistry with Wendell Meredith Stanley "for their preparation of enzymes and virus proteins in a pure form."…

2000 CE

#11981

Cultivation of the bacillus of Whipple's disease.

Order of authorship in the original publication: Raoult, Birg, La Scola. Raoult and colleagues cultured the bacterium causing the systemic digestive tract infection Whipple's disease from a mitral valve of a patient w…

2006 CE

#11982

Culture of T. whipplei from the stool of a patient with Whipple's disease.

Order of authorship in the original publication: Raoult, Fenollar, Birg. Raoult and colleagues cultured the infectious agent of Whipple's disease from the stool of a patient with the disease. In the process the author…

1887 CE

#1018

D’une disposition à sphincter spéciale de l’ouverture du canal cholédoque.

“Sphincter of Oddi” of the bile duct, already known to Glisson in 1654. Reprinted as a pamphlet, Perugia, 1887.

1884 CE

#3480

Darmresektion und Enterorhaphieen, 1878-83.

Billroth was a pioneer in visceral surgery. Above is an account of many intestinal resections and enterorrhaphies carried out by him.

1936 CE

#3659.2

Das Coeliakiesyndrom bei angeborener zysticher Pankreasfibromatose und Bronchiektasien.

Cystic fibrosis (mucoviscidosis) described. With E. Uehlinger and C. Knauer.

1864 CE

#3461

Das perforirende Geschwür im Duodenum.

The first comprehensive study of duodenal ulcer. Commercial edition, Berlin: A. Hirschwald, 1865. Digital facsimile of the 1864 edition from the Bayerische Staatsbibliothek at this link. Digital facsimile of the 1865 …

1745 CE

#978

De fabrica et actione villorum intestinorum tenuium hominis.

“Lieberkühn’s glands” or “crypts” described. They were discovered by Malpighi in 1688.

1687 CE

#975

De glandulis in intestino duodeno hominis detectis.

“Brunner’s glands”, earlier described by Wepfer (No. 974.1).

1879 CE

#3472

De l’ablation des tumeurs de l’estomac par la gastrectomie.

First gastrectomy for carcinoma; unsuccessful.

1819 CE

#2673

De l’auscultation médiate, ou traité du diagnostic des maladies des poumons et du coeur. 2 vols.

This book revolutionized the study of diseases of the chest. Auscultation in the instrumental sense dates from Laennec’s invention of the stethoscope (at first merely a roll of stiff paper) with a view to amplif…

1848 CE

#995

De l’origine du sucre dans l’économie animale.

Bernard’s first communication regarding his investigation of the glycogenic function of the liver. Reprinted, with translation, in Med. Classics, 1939, 3, 552-80.

1586 CE

#3417

De medica historia mirabili.

An early history of diseases, with extensive sections on ophthalmology (ff. 66-77) and urology (ff. 260-271). Lib. IV, Cap. iii, page 196 contains the first recorded case of gastric ulcer. Lib. VI. cap. iii contains t…

1742 CE

#3423

De mutuo intestinorum ingressu.

First recorded successful operation for intussusception in an adult. The paper is also included in Haller’s Disputationes, vol. 1.

1746 CE

#3424

De ruptura intestini duodeni.

First description of duodenal ulcer.

1664 CE

#974

De succi pancreatici natura et usu exercitatio anatomico-medica.

De Graaf was an early investigator of the pancreatic secretion. He collected the pancreatic juice of dogs by means of artificial pancreatic fistulae, commenting on the small quantity of juice secreted and on its alkal…

1930 CE

#1038

Demonstration of the humoral agent in fat inhibition of gastric secretion.

The work of Kosaka and Lim led to the discovery of a hormone inhibiting gastric secretion (“enterogastrone”).

1958 CE

#3558.3

Demonstration of the new gastroscope, the “fiberscope”.

The Hirschowitz fiber optic endoscope, the "Fiberscope." In February 1957 Hirschowitz passed the first prototype instrument down his own throat and, a few days later, down that of a patient. Hirschowitz gave the first…

1891 CE

#3633

Der Icterus und seine verschiedenen Formen.

1883 CE

#1015

Der Schluckmechanismus, seine Erregung und seine Hemmung.

An experimental study, by means of a balloon, of swallowing and of oesophageal contractions.

1888 CE

#3492.1

Des polyadénomes gastriques et de leurs rapports avec le cancer de l’estomac.

“Menetrier’s disease” – giant hypertrophic gastritis.

1858 CE

#3457

Description of the operation of gastrotomy.

First gastrostomy in Britain.

1919 CE

#3651

Diagnosis and treatment of diseases of the gall-bladder and bilary ducts. Preliminary report on a new method.

See No. 3649.

1890 CE–1893 CE

#3497

Diagnostik und Therapie der Magenkrankheiten. 2 pts.

Boas, who devised the test breakfast, became the foremost gastroenterologist in Europe. He founded the Archivfür Verdauungskrankheiten, the first journal devoted to the subject of gastroenterology.

1914 CE

#1032

Die äussere Sekretion der Verdauungsdrüsen.

1909 CE

#3645

Die Cholelithiasis.

1886 CE

#1017

Die Darmbakterien des Säuglings und ihre Beziehungen zur Physiologie der Verdauung.

Includes the first account of Bact. coli infection. The organism was later renamed Escherichia coli (E.coli).

1928 CE

#3546

Die Entzündungen des Magens. In: F. Henke & O. Lubarsch: Handbuch der speziellen pathologischen Anatomie und Histologie, 4, Heft 2, 768-1116.

Konjetzny suggested that peptic ulceration is the sequel to a specific form of gastritis.

1889 CE

#3495

Die Gastrodiaphanie.

Einhorn devised the method of exploration of the stomach by means of a tube – gastrodiaphany.

1911 CE

#3535.1

Die Gastroskopie.

Elsner designed a straight gastroscope with a rubber tip and an optical system to be pushed into the outer tube, which had a lamp at its tip.

1902 CE

#1025

Die Gesetze des Energieverbrauchs bei der Ernährung.

Rubner’s classic work on the influence of foodstuffs on metabolism. In it he introduced the term “specific dynamic action of the foodstuffs”.

1959 CE–1967 CE

#3666.6

Die historischen Grundlagen der Leberforschung. 2 vols.

1968 CE

#3666.7

Die Leber und ihre Krankheiten. Zweihundert Jahre Hepatologie.

Contains short biographies and an excellent bibliography.

1876 CE

#3467.1

Die partielle Magenresektion; eine experimentelle operative Studie.

A practical method for excision of the pylorus, as demonstrated in dogs, was published by these two assistants of Billroth.

1850 CE

#997

Die Physiologie der Nahrungsmittel.

1826 CE–1827 CE

#988

Die Verdauung nach Versuchen. 2 vols.

Confirmation of the work of Prout.

1852 CE

#999

Die Verdauungssäfte und der Stoffwechsel.

Even after the work of Prout and Beaumont, some physiologists thought that the free acid of the gastric juice was lactic acid; Bidder and Schmidt finally proved that normally the gastric juice always contains HCl in e…

1903 CE

#3641

Disease of the pancreas; its cause and nature.