Facets

1825 CE

#2210

Collections from the unpublished writings of the late Caleb Hillier Parry. 3 vols.

Includes Parry’s interesting description of eight cases of exophthalmic goitre, the first of which was observed in 1786, and his notes on four cases of angina pectoris. Parry's paper, "Enlargement of the thyroid…

1970 CE

#2660.24

Combination chemotherapy in the treatment of advanced Hodgkin’s disease.

Combination chemotherapy with nitrogen mustard (mustine hydrochloride), vincristine sulphate, procarbazine hydrochloride and prednisone, introduced in 1964 for the treatment of advanced Hodgkin’s disease. With A…

1823 CE

#1492.1

Commentatio de examine physiologico organi visus et systematis cutanei.

Purkynĕ was first to examine the interior of the human eye and the dog eye, using only a candle and a concave spherical lens. He thus invented the ophthalmoscope three decades before Helmholtz (1851; No. 5866). Reprin…

1829 CE

#9472

Comments on corpulency, lineaments of leanness ....

The first illustrated book on obesity research or medical efforts to control overweight. Wadd, one of the surgeons extraordinary to George IV, drew and engraved the illustrations himself. Digital facsimile from the In…

1949 CE

#4154.2

Concurrent melanosis and hypertrichosis in distribution of nevus unius lateris.

“Becker’s nevus”, pigmented hairy epidermal nevus.

1886 CE

#3790

Congenital absence of hair and mammary glands with atrophic condition of the skin and its appendages in a boy whose mother had been almost wholly bald from alopecia areata from the age of six.

First description of progeria.

1971 CE

#534.71

Congenital malformations. Notes and comments.

Warkany's contributions span all aspects of teratology, both clinical and experimental. This has been called his magnum opus. It includes 124 chapters, each with detailed bibliography, on a total of 1271 pages.

1933 CE

#2899

Congestive heart failure and angina pectoris: The therapeutic effect of thyroidectomy on patients without clinical or pathologic evidence of thyroid toxicity.

Thyroidectomy for congestive heart failure and angina pectoris. With D. D. Berlin.

2003 CE

#10709

Conjoined twins: An historical, biological and ethical issues encyclopedia.

1933 CE–1939 CE

#6131

Considérations sur la radiothérapie des cancers cervico-uterins, d’après l’experience et les résultats acquis à l’Institut du Radium de Paris.

The Paris method of radium treatment of cancer of the uterus was devised by Regaud.

1975 CE

#2578.43

Continuous cultures of fused cells secreting antibody of predefined specificity.

Hybridomas. In 1984 Köhler and Milstein shared the Nobel Prize in Physiology or Medicine with Niels K. Jerne, "for theories concerning the specificity in development and control of the immune system and the disco…

1977 CE

#2662.3

Contrary to nature. Being an illustrated commentary on some persons and events of historical importance in the development of knowledge concerning cancer.

1930 CE

#3973

Contribución al estudio sobre la composición quimica de la insulina. Estudio de algunos cuerpos sintéticos solfurados con acción hypoglucemiante.

Discovery of the hypoglycemic effect of certain sulphonamide derivatives. With L. L. Silva and L. Libenson.

1895 CE

#2547

Contribution à l’ étude du sérum chez les animaux vaccinés.

In Bordet’s classic paper on the properties of the sera of immunized animals he showed that two different substances (now known as sensitizing antibody and complement) are involved in the phenomenon of bacteriol…

1888 CE

#3630

Contribution à l’étude clinique et anatomo-pathologique du cancer primitif du pancréas.

“Bard-Pic syndrome” first described.

1894 CE

#5063

Contribution à l’étude de la diphtérie (sérum thérapie).

Roux and Martin demonstrated the value of Behring’s specific antitoxin in the treatment of human diphtheria, and showed how it could be produced on a large scale.

1888 CE–1889 CE

#5059

Contribution a l’étude de la diphtérie.

Confirmation of the work of Loeffler and demonstration of the exotoxin. This work is the starting point of the development of an immunizing serum.

1907 CE

#2597

Contribution à l’étude du “phénomène d’Arthus.”

“Passive” anaphylaxis first demonstrated.

1887 CE

#3836

Contribution à l’étude du myxoedème consécutif à l’extirpation totale ou partielle du corps thyroïde.

1884 CE

#3946

Contribution à l’étude du pancreas du lapin. Lésions provoquées par la ligature du canal de Wirsung.

Arnozan and Vaillard showed that blockage of the pancreatic ducts caused atrophy of the pancreas but not diabetes.

1894 CE

#2107

Contribution à l’étude du vénin des serpents.

Calmette carried out extensive investigations on the immunization of animals to venoms. He obtained antivenom sera with therapeutic properties.

1899 CE

#3639.1

Contribution to the surgery of the bile passages, especially of the common bile-duct.

“Among Halsted’s many outstanding surgical accomplishments those related to surgery of the biliary tract are lesser known. However, he is commonly credited with performing the first successful operation fo…

1951 CE

#2660.3

Contributions to the study of marine products. XXXII. The nucleosides of sponges.

Cytosine arabinoside, a pyramidine antagonist, used in acute myeloblastic anemia.

1900 CE–1908 CE

#516

Contributions to the study of the pathology of early human embryos. 3 pts. : (1). A contribution to the study of the pathology of early human embryos. Welch Festschrift, Johns Hopkins Hospital Reports, IX (1900). (2). Second contribution to the study of the pathology of early human embryos. Contributions to medical research. Dedicated to Victor C. Vaughan. Ann Arbor (1903). (3). A study of the causes underlying the origin of human monsters. Third contribution to the study of the pathology of human embryos. Reprinted from Journal of morphology, 29, No. 1 (1908).

Part 3, with 365 pages and illustrations was the main work of this series. Mall began the introduction to the third part as follows: "The present communication is the outcome of a study of 163 pathological human embry…

1893 CE

#4114

Contributo allo studio della ipercheratosi dei canali sudoriferi (porokeratosis).

Mibelli is sometimes credited with the original description of porokeratosis (“Mibélli’s disease”), but Neumann described it in 1875 under the name of “dermatitis circumscripta herpetifo…

1976 CE

#14222

Correlation of glucose regulation and hemoglobin AIc in diabetes mellitus.

The authors studied 5 diabetic patients and first realized that A1c was an ideal index to reveal the overall control of a patient’s blood sugar over the past several months before a doctor’s visit. They we…

1968 CE

#12038

Correspondence of Pasteur & Thuillier concerning anthrax and swine fever vaccinations. Translated and edited by Robert M. Frank and Denise Wrotnowska. Preface by Louis Pasteur Vallery-Radot.

Edition and translation of about 60 letters mostly between Pasteur and his protegé Louis Thuillier in the Reynolds Historical Library at the University of Alabama. During the period involved in this corresponde…

1937 CE

#1154

Corticosteron, a crystallized compound with the biological activity of the adrenal-cortical hormone.

Isolation of corticosterone. With E. Laqueur, T. Reichstein, R. W. Spanhoff, and I. E. Uyldert.

1844 CE–1845 CE

#267.1

Cours de microscopie. 1 vol. and atlas.

Donne's and Foucault's work was the first biomedical textbook to be illustrated with images made from photomicrographs, in this case daguerreotypes of blood cells. Among its noteworthy images are the first microphotog…

2020 CE

#13484

COVID-19 vaccine development and a potential nanomaterial path forward.

Published 15 July 2020. Order of authorship in original publication: Shin, Shukla, Chung....Steinmetz. Probably the first publication on the type of nanotechnology involved in production of the Moderna and Pfizer mRNA…

1922 CE

#3871

Crises solaires et hypertension paroxystique en rapport avec une tumeur surrénale.

First full description of chromaffin cell tumors of the adrenal medulla. With J. Tinel and E. Doumer.

2007 CE

#11843

CRISPR provides acquired resistance against viruses in prokaryotes.

Horvath and his team provided key details of the extremely complex mechanisms involved in CRISPR's function as an immune system for bacteria against bacteriophages. Analogous to Pasteur's heroic role in saving the Fre…

2020 CE

#13483

Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.

Posted online on February 17, 2020. 2019-nCoV was an interim name for the Novel Coronavirus. These studies, which included the 3D structure of the RBD (receptor binding domain) within the S protein, provided informati…

1926 CE

#1206

Crystalline insulin.

Crystalline insulin first obtained. See also J. Pharmacol., 1927, 31, 65-85.

1964 CE

#2660.17

Cultivation in vitro of human lymphoblasts from Burkitt’s malignant lymphoma.

Order of authorship in the original publication: Epstein, Barr. Discovery of the Epstein-Barr virus, a human herpes virus causing infectious mononucleosis, and implicated in Burkitt’s lymphoma and other forms of…

1945 CE

#5399

Cultivation of Rickettsia tsutsugamushi in lungs of rodents. Preparation of a scrub-typhus vaccine.

Scrub-typhus vaccine.

1949 CE

#4671.1

Cultivation of the Lansing strain of poliomyelitis virus in cultures of various human embryonic tissues.

Enders, Weller, and Robbins grew the poliomyelitis virus in cultures of different tissues. Their method proved of great value in virus research, and removed the final obstacles to vaccine production. In 1974 Enders, W…

1910 CE

#2636

Cultures de sarcome en dehors de l’organisme.

Using the Rous chicken sarcoma, Carrel and Burrows were the first to grow tumor tissue in vitro.

1901 CE

#4132

Cutis laxa. Neigung zu Haemorrhagien in der Haut, Lockerung mehrerer Artikulationen.

Description of the syndrome to which the name “Ehlers–Danlos syndrome” was later attached (see also No. 4144), earlier described by Tschernogubow: Cutis laxa, Mh. prakt. Derm., 1892, 14, 76.

1954 CE

#2660.7

Cytoactive amino-acid and peptide derivatives. I. Substituted phenylalanines.

Melphalan (a nitrogen mustard) later used in the chemotherapy of cancer.

1964 CE

#2660.19

Cytology of Burkitt’s tumour (African lymphoma).

1866 CE

#4056

Das Colloid-Milium der Haut.

Colloid degeneration of the skin (“Wagner’s disease”) was first described by Wagner who gave it the name “Colloid milium”.

1927 CE

#1168

Das Hormon des Hypophysenvorderlappens.

Isolation of the gonadotrophic hormone of the anterior pituitary (Prolan A & B).

1909 CE

#3963

Das Koma diabeticum und seine Behandlung.

Magnus-Levy is remembered for his work on the treatment of diabetic coma.

1872 CE

#3767

Das maligne Lymphosarkom (Pseudoleukämie).

Langhans noted the presence of giant cells in the lesions of Hodgkin’s disease.

1918 CE

#3849

Das Myxödemherz

First systematic study of the characteristic changes of the heart in myxedema.

1907 CE

#6118

Das Oophoroma folliculare.

“Brenner tumor”, earlier described by Orthmann (No. 6109). See the historical note in Cancer, 1956, 9, 217.

1924 CE

#562

Das reticulo-endotheliale System.

In an earlier paper on this subject (Münch, med. Wschr., 1922, 69, 1352-56) Aschoff introduced the term “reticulo-endothelial system”; as early as 1914 he grouped certain phagocytic cells into his sys…

1885 CE

#2540

Das Sauerstoff-Bedürfniss des Organismus. Eine farbenanalytische Studie.

Includes the first statement of Ehrlich’s “side-chain” theory.

1887 CE

#4092

Das seborrhoische Ekzem.

Unna’s seborrhoeic eczema.