Facets

1910 CE

#848

Ueber die Folgen der Durchschneidung der Tawaraschen Schenkel der Reizleitungssystems.

First experimental study of the electrocardiographic changes in bundle-branch block. "Later, as professor and director of the internal clinic at the Allgemeines Krankenhaus in Vienna, Eppinger became one of the most n…

1837 CE

#929

Ueber die im Blute enthaltenen Gase, Sauerstoffe, Stickstoff, und Kohlensäure.

First quantitative analysis of the blood gases. Magnus proved that the arterial blood contains a higher concentration of oxygen than venous blood and that the latter had a higher carbon dioxide content.

1902 CE

#893

Ueber die Isoagglutinine im Serum gesunder und kranker Menschen.

Following Landsteiner’s division of human blood into three groups (A, B and O which he named A, B, C), Decastello and Sturli discovered a fourth (the rarest) group, later named AB.

1880 CE

#2783

Ueber die pathologische Gerinnungs-Vorgänge.

First description (p. 106) of myocardial infarction. Leibowitz called this "the most significant contribution by a pathologist to the history of coronary heart disease." He also wrote, "This work not only provides a g…

1903 CE

#2911

Ueber die reine Mediaverkalkung der Extremitätenartien und ihr Verhalten zur Arteriosklerose.

“Mönckeberg’s sclerosis”. He described a form of medial sclerosis of the blood-vessels of the extremities. See also his later papers in Klin. Wschr.,1942, 52,1473-78, 1521-26.

1884 CE

#2907.1

Ueber die Sclerose der coronar-Arterien und die davon abhängigen Krankheitszustände.

A comprehensive account of the schlerosis of the coronary arteries and the morbid states arising from them, including a historical review of the problems.

1904 CE

#2815

Ueber die syphilitischen Aortenerkrankungen.

1904 CE

#1893.1

Ueber Digalen (Digitoxinum solubile).

Introduction of digalen.

1879 CE

#6338

Ueber eine bisher nicht beschriebene endemisch aufgetretene Erkrankung Neugeborener.

First description of “Winckel’s disease” of the newborn, characterized by icterus, hemorrhage, hemoglobinuria, and cyanosis.

1866 CE

#2906

Ueber eine bisher noch nicht beschriebene eigenthümliche Arterienerkrankung (Periarteritis nodosa), die mit Morbus Brightii und rapid fortschreitender allgemeiner Muskellähmung einhergeht.

First description of periarteritis nodosa.

1879 CE

#2907

Ueber eine eigenthümliche Form von Endarteriitis und Endophlebitis mit Gangrän des Fusses.

Early description of thromboangiitis obliterans (Buerger’s disease, No. 2912).

1903 CE

#3074

Ueber eine Methode zur Untersuchung des lebenden Knochenmarks von Thieren und über das Bewegungsvermögen der Myelocyten.

Wolff-Eisner trephined the tibia and femur of experimental animals and suggested biopsy of bone marrow as a clinical procedure.

1913 CE

#3082.1

Ueber eine neue Leukämie durch echte Uebergangsformen (Splenozytenleukämie) und ihre Bedeutung für die Selbständigkeit dieser Zellen.

Monocytic leukemia reported.

1888 CE

#3129

Ueber einen Fall von Anämie mit Bemerkungen über regenerative Veränderungen des Knochenmarks.

Ehrlich was first to distinguish the aplastic type of anemia.

1904 CE

#726

Ueber einen in biologischer Beziehung wichtigen Einfluss, den die Kohlensäurespannung des Blutes auf dessen Sauerstoffbindung übt.

Bohr, Hasselbalch, and Krogh showed, in the experimental animal, that the affinity of blood for oxygen depends upon carbon dioxide pressure. This became known as the Bohr effect, though the discovery may have been mad…

1866 CE

#2764.1

Ueber einen sehr seltenen Fall von Insufficienz der Valvula tricuspidalis, bedingt durch eine angeborene hochgradige Missbildung derselben.

“Ebstein’s anomaly,” a congenital abnormality of the tricuspid valve. Translation in Amer. J. Cardiol, 1968, 22, 867-72.

1852 CE

#2904

Ueber einige der wichtigsen Krankheiten der Arterien.

One of Rokitansky’s best works. He described atheroma and calcification in the intima of arteries, and various congenital malformations. Rokitansky "is credited with the initial case report of polyarteritis nodo…

1913 CE

#2915

Ueber experimentelle Cholesterinsteatose und ihre Bedeutung für die Entstehung einiger pathologischer Prozesse.

Anichkov and Chalatov of St. Petersburg, Russia, discovered that atherosclerosis of large arteries is critically dependent on cholesterol. (Translated in Arteriosclerosis, 1983, 3, 178-182). The inflammatory nature of…

1856 CE

#3064

Ueber farblose Blutkörperchen und Leukämie. In his Gesammelte Abhandlungen zur wissenschaftlichen Medicin, pp. 147-218.

Includes his paper on “weisses Blut” (see No. 3062) and three later papers on leukemia. See No. 3006.

1882 CE

#2786

Ueber Fettherz.

Fatty infiltration of the heart first described.

1889 CE

#3916

Ueber Haemochromatose.

Recklinghausen gave to hemochromatosis its present name.

1871 CE

#3122

Ueber hochgradigste Anämie Schwangerer.

An important account of pernicious anemia of pregnancy.

1889 CE

#3131

Ueber Leukaemia und Leukocytose im Kindesalter.

From this classic description of infantile pseudoleukemic anemia, the condition became known as “von Jaksch’s disease”.

1902 CE

#2813

Ueber orthodiagraphische Untersuchungen am Herzen.

Orthodiagraphy of the heart.

1884 CE

#3128

Ueber progressive perniciöse Anämie bei Tabeskranken

First description of subacute combined degeneration of the spinal cord, which Leichtenstern termed progressive pernicious anemia in tabetics.

1887 CE

#3068

Ueber Purpura fulminans.

First description.

1862 CE

#814

Ueber Reflexionen von und zum Herzen (Klopfversuch).

Rapidly-repeated blows on the belly of a frog caused cessation of the heart-beat, which Goltz concluded was brought about by reflex inhibition through the vagus, an important contribution to the knowledge of the mecha…

1873 CE

#2776

Ueber schwielige Mediastino-Pericarditis und den paradoxen Puls.

Kussmaul introduced the concept of the “paradoxical pulse.”

1906 CE

#2824

Ueber Spirochaeta pallida in der Aortenwand bei Hellerscher Aortitis.

Treponema pallidum first discovered in the diseased aorta.

1910 CE

#898

Ueber Vererbung gruppenspezifischer Strukturen des Blutes.

Proof that blood groups are inherited according to Mendelian laws.

1918 CE

#2848

Ueber Vorhofflimmern beim Menschen und seine Beseitigung durch Chinidin.

Following Wenckebach’s discovery of the efficacy of quinine in the restoration of normal rhythm in auricular fibrillation. Frey showed that quinidine was the most effective of the cinchona alkaloids in this resp…

1872 CE

#2773

Ueber zwei seltene Herzaffektionen, mit Bezugnahme auf die Theorie des ersten Herztons.

“Bamberger’s disease” (Pick’s disease, No. 2803).

1896 CE

#5212

Ulcerative endocarditis due to the gonococcus; gonorrheal septicemia.

Thayer and Blumer found the gonococcus in cases of gonorrheal endocarditis.

1957 CE

#2883.21

Ultrasonic Doppler method for the inspection of cardiac functions.

Demonstration of the Doppler shift in the frequency of ultrasound backscattered by moving cardiac structures.

1901 CE

#840

Un nouveau galvanomètre.

Einthoven directed much of his research to the development and perfection of recording instruments. His most famous work was in connexion with his string galvanometer, a perfection of the instrument invented by J. S. …

1896 CE

#2804

Un nuovo sfigmomanometro.

Riva-Rocci’s sphygmomanometer marked the end of the search for a simple clinical method of estimating the blood-pressure. Abridged English translation in Ruskin (No. 3160.1).

1875 CE–1876 CE

#877

Undersökningar af de s.k. fibringeneratorema fibrinet samt fibrinogenets koagulation.

Investigating the mechanism of blood coagulation, Hammarsten showed it to be accomplished by the splitting up of fibrinogen into fibrin and other substances.

1944 CE

#2028

Untersuchungen über Dextran und sein Verhalten bei parenteraler Zufuhr.

Introduction of dextran as plasma substitute.

1872 CE

#3010

Untersuchungen über die embolischen Processe.

Cohnheim developed the doctrine of infarction as a result of occlusion of terminal arteries. He explained the haemorrhagic nature of certain infarcts on the basis of a reflux flow and diapedesis through the altered ca…

1848 CE

#2979

Untersuchungen über die Natur der krankhaften Veränderungen der Arterienwände, die als Ursachen der spontanen Aneurysmen zu betrachten sind.

1875 CE

#1869.1

Untersuchungen über die pharmakologisch wirksamen Bestandtheile der Digitalis purpurea

Schmiedeberg isolated digitoxin from digitalis.

1959 CE

#3047.13

Ventricular aneurysm following myocardial infarction: Results of surgical treatment.

Cardiopulmonary bypass and open excision of the aneurysm. With W.S. Henly, K.H. Amad, & D.W. Chapman.

1947 CE

#2878.1

Ventricular fibrillation of long duration abolished by electric shock.

The first successful defibrillation of a surgical patient, with the chest opened, and the paddles applied directly to the heart. With H.S. Feil.

1920 CE

#2853

Verhandlungen ärtzlicher Gesellschaften und Kongressberichte.

Saxl injected a mercurial compound (Novasurol), a powerful diuretic, for the treatment of cardiac failure.

1667 CE

#2972

Vesalius: Una cum D. Bartholomaei Velseri literis, Tuas, doctissime et mihi amicissime D. Achilles, accepi.... IN: Welsch, G. H., Sylloge curationum et observationum medicinalum centurias vi complectens (J. U. Rumler, Observationes medicae e bibliotheca Georgi Hieronymi Velschii, cum eius dem notis LXXXXI, p. 47).

In 1555 Vesalius was the first to diagnose an aneurysm of the thoracic and abdominal aorta in a living person. Vesalius wrote this consilium to Achilles Pirmin Gasser on July 18, 1557; it was not published until more …

1949 CE

#3155

Vitamin B12 in pernicious anaemia: parenteral administration.

1820 CE

#3056

Von einer erblichen Neigung zu tödtlichen Blutungen.

In his description of hemophilia Nasse stressed the immunity of females, despite their ability to transmit the disease. This fact has become known as “Nasse’s law”.

1909 CE

#2831

Vorhofflimmern und Arhythmia perpetua.

Independently of Lewis (No. 2830) these workers claimed auricular fibrillation to be the cause of perpetual arrhythmia.

1877 CE–1880 CE

#2303

Vorlesungen über allgemeine Pathologie. 2 vols.

Apart from Virchow’s Cellularpathologie, this was the most influential textbook of pathology during the 19th century. It includes (vol. 1, p. 38) a report on the experimental production of heart murmurs. English…

1845 CE

#3062

Weisses Blut.

Only six weeks after Bennett, Virchow independently published a report on the necropsy of a case of leukemia. He gave the condition its present name. For translation, see Major, Classic descriptions of disease, 3rd. e…