Facets

1920 CE

#86.2

Papers and addresses by William Henry Welch. [Edited by Walter C. Burket]. 3 vols.

Vol. 1: Pathology and preventive medicine. Vol. 2: Bacteriology. Vol. 3: Medical education, history, miscellaneous subjects, and Welch's bibliography. Introduction by Simon Flexner. Digital facsimile from the Internet…

2009 CE

#12665

Papillomavirus vaccines. US Patent US7476389B1.

Frazer and Zhou invented and patented the first Papillomavirus vaccine. In 2020 it was marketed as Gardasil and Cervarix. Developed beginning in 1991, about 20 years after Blumberg and Millman's vaccine against viral …

2013 CE

#10219

Paralysed with fear: The story of polio.

1959 CE

#10676

Parasites and parasitic infections in early medicine and science.

1964 CE

#11672

Parasites of the human heart.

1969 CE

#10675

Parasitic diseases in Africa and the Western Hemisphere. Early documentation and transmission by the slave trade.

1968 CE

#6840

Particles associated with Australia antigen in the sera of patients with leukemia, Down's syndrome and hepatitis.

Particles with the appearance of a virus were detected by electron microscopy in the serum of individuals with Au. These were subsequently shown to be the surface antigen particles, different from the whole virus part…

1975 CE

#11190

Parvovirus-like particles in human sera. Preliminary communication.

Order of authorship in the original paper: Cossart, Field, Cant. First description of Parvovirus B19, the first human parvovirus discovered. It is among the smallest DNA viruses and is most often known for causing dis…

2018 CE

#11480

Pathogen elimination by probiotic Bacillus via signaling interference.

Order of authorship in the original publication: Piewngam, Zheng, Nguygen....The authors discovered a mechanism by which probiotics help maintain a healthy microbiome. They showed that Bacillus subtilis can produce a …

1948 CE

#5261.2

Pentaquine (Sn-13,276), a therapeutic agent effective in reducing the relapse rate in vivax malaria.

Clinical trials of pentaquine. With B. Craige, R. Jones, C. M. Whorton, T. N. Pullman, and L. Eichelberger.

1892 CE

#5528.2

Pentastomas.

Posadas (No. 5528.1) and Wernicke, a professor pathology in Buenos Aires, were the first to report cases of coccidioidomycosis. German translation of Wernicke’s paper in Zbl. Bakt., 1892, 12, 859-61.

1908 CE

#9018

Philumeni de venenatis animalibus eorumque remediis capita XXXVIII ed. M. Wellmann. Corpus medicorum graecorum X 1, 1.

This work on venoms and their antidotes is the only surviving work of the Byzantine physician Philomenos. Within this context Philomenos also discusses the bites of rabid dogs. Digital facsimile from Corpus medicorum …

1887 CE

#10596

Photography of bacteria. Illustrated with eight-six photographs reproduced in autotype.

The first book entirely devoted to the photography of bacteria. Digital facsimile from Google Books at this link.

1977 CE

#12300

Phylogenetic structure of the prokaryotic domain: The primary kingdoms.

(Order of authorship in the original publication: Woese, Fox.) Woese and Fox discovered a "third kingdom" in microbial life that they called "archaebacteria" (Archaea) as distinct from bacteria and eukaryotes. In thei…

1821 CE

#10647

Phytographie médicale, ornée de figures coloriées de grandeur naturelle, ou l’on expose l’histoire des poisons tirés du règne végétal, et les moyens de remédier a leurs effets délétères, avec des observations sur les propriétés et les usages des plantes héroïques. 2 vols.

Perhaps the most beautiful book on botanic poisons and their antidotes, including narcotics. Plates 1-15 cover mushrooms, and plate 175 depicts Cannabis sativa. With 180 plates printed in color à la poup&eacute…

1846 CE

#4039

Pilzbildung in der Pityriasis versicolor.

Eichstedt discovered Pityrosporum orbiculare, fungus of pityriasis versicolor (“Eichstedt’s disease”).

1957 CE

#10886

Piroplasmosis in man: Report on a case.

Order of authorship in the original paper was Škrabalo, Deanovic. First report of a case of babesiosis in a human, in this case an immunocompromised patient in Zagreb, (now Croatia). Piroplasmosis is another te…

1856 CE

#4044

Pityriasis pilaris, maladie de peau non décrite par les dermatologistes.

Devergie is remembered for his clear description of pityriasis rubra pilaris, (“Devergie’s disease”). He was the first to demonstrate the presence of a fungus in eczema marginatum.

1954 CE

#14000

Plaque formation and isolation of pure lines with poliomyelitis viruses.

Dulbecco and Vogt were the first to successfully grow the poliovirus in vitro. They were also able to plaque purify it-- an essential step for subsequent vaccine production.

1988 CE

#2581.13

Portraits of viruses: A history of virology.

Well-documented essays on specific families of viruses by expert researchers, reprinted from Intervirology, 1979, 11-1986, 26.

1909 CE

#5283.1

Positive Infektionsversuche mit Trypanosoma brucei durch Glossina palpalis.

Glossina was believed to transmit Trypanosoma mechanically to the new host until Kleine showed that the latter undergoes a developmental cycle in Glossina. English translation in Kean (No. 2268.1).

1962 CE

#10920

Powassan virus: Field investigations in Northern Ontario, 1959-1961.

The authors isolated a virus from the brain of a child who died of encephalitis in Powassan, Ontario, and named it the Powassan virus. They posited a tick vector and possible rodent natural hosts. (Thanks to Juan Weis…

1818 CE

#5182.1

Practical observations on fever, dysentery and liver complaints as they occur amongst European troops in India. With introductory remarks on the disadvantages of selecting boys for Indian military service.

Ballingall distinguished between amoebic and bacillary dysentery. Digital facsimile from the Internet Archive at this link.

1843 CE

#8807

Practical observations on the principal diseases affecting the health of the European and native soldiers in the north-western provinces of India with a supplement on dysentery.

Digital facsimile from the Internet Archive at this link.

1846 CE–1847 CE

#5026

Practical remarks on the continued fevers of Great Britain, and on the generic distinctions between enteric fever and typhus.

Introduction of the term “enteric fever”, a term for typhoid. Ritchie carefully differentiated the symptoms of typhus and typhoid.

1892 CE

#2545.1

Practical results of bacteriological researches.

Sternberg demonstrated that the serum of an animal recovered from vaccinia possesses the property of neutralizing the activity of the causative virus. His test was readily adaptable for use in various host-systems.

1791 CE

#5833.2

Praktische Beobachtungen über verschiedene, vorzüglich aber über jene Augenkrankheiten, welche aus allgemeinen Krankheiten des Körpers entspringen.

“This is the first monograph ever published dealing with ocular signs of systemic disease. It deals with lacrimal fistulas, trichiasis, adhesions of the lids, lid ulcers, ephiphora, and ocular inflammations. He …

1932 CE

#5351.1

Precipitin and skin tests as aids in diagnosing trichinosis.

Intradermal test for trichinosis.

1902 CE

#5275

Preliminary note upon a trypanosome occurring in the blood of man.

Dutton was the first to recognize human trypanosomiasis. He saw Forde’s patient (see No. 5274) and named the trypanosome T. gambiense. Sleeping sickness itself has been referred to as “Dutton’s disea…

1889 CE

#10885

Preliminary observations on the microorganism of Texas fever.

First report on the discovery of a Babesia, cause of Babesiosis. Smith first observed the microscopic organism in the summer of 1886, but mentioned Babes's work in this paper, perhaps resulting in Babes being credited…

1980 CE

#11257

Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae.

Discovery of the pathogenic relationship between amoebas and Legionella bacteria--a key step in understanding how this bacteria infects mankind. Legionella bacteria, along with amoeba, live in the organic contaminatio…

2014 CE

#11341

Presence of extensive Wolbachia symbiont insertions discovered in the genome of its host Glossina morsitans morsitans.

Order of authorship in the original publication: Brelsfoard, Tsiamis, Falchetto....The authors suggested that infection by Wolbachia may give a reproductive advantage to the fly that carries the parasite causing Sleep…

1981 CE

#9176

Primary structure, gene organization and polypeptide expression of poliovirus RNA.

The poliovirus genome. With around 10 co-authors. "The primary structure of the poliovirus genome has been determined. The RNA molecule is 7,433 nucleotides long, polyadenylated at the 3′ terminus, and covalentl…

1952 CE

#13999

Production of plaques in monolayer tissue cultures by single particles of an animal virus.

Following Max Delbruck's advice, Dulbecco visited the major centers of animal virus work in the US in order to discover a way to quantitatively assay animal viruses by a plaque technique, similar to the technique that…

1955 CE

#5546.3

Propagation and primary isolation of mumps virus in tissue culture.

1956 CE

#2527.2

Propagation in tissue culture of a cytopathogenic virus from human salivary gland virus (SGV) disease.

Isolation of cytomegalovirus

1962 CE

#5509.1

Propagation in tissue culture of cytopathic agents from patients with rubella-like illness.

Isolation of rubella virus. It was simultaneously isolated by P. D. Parkman, et al. (No. 5509.2.)

1954 CE

#5449.2

Propagation in tissue cultures of cytopathogenic agents from patients with measles.

Isolation of measles virus.

1936 CE

#5484.2

Propagation of rabies virus in tissue culture and the successful use of culture virus as antirabic vaccine.

Webster and Clow succeeded in growing rabies virus in tissue culture.

1935 CE

#5496

Propagation of the virus of epidemic influenza on the developing egg.

Cultivation of the influenza virus.

2017 CE

#10906

Proposal to reclassify Ehrlichia muris as Ehrlichia muris subsp. muris subsp. nov. and description of Ehrlichia muris subsp. eauclairensis subsp. nov., a newly recognized tick borne pathogen of humans.

Order of authorship in the original publication: Pritt, Allderdice, Sloan. By extremely complex genotyping methods and fine electron microscopic analysis of the organism, the authors showed that the infectious agent i…

2016 CE

#11375

Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody.

The cited paper was immediately followed in the same issue of Science by: John Misasi, Morgan A. Gilman, Masaru Kanekiyo et al, "Structural and molecular basis for Ebola virus neutralization by protective human antibo…

1903 CE–1915 CE

#2458

Protozoa and disease. 4 vols.

1926 CE

#2462

Protozoology. 2 vols.

Wenyon was one of the world’s foremost authorities on medical protozoology.

1915 CE

#5430.1

Pure cultivation in vivo of vaccine virus free from bacteria.

Noguchi obtained a pure culture of vaccinia virus.

1912 CE

#2519

Pure cultivation of Spirochaeta refringens.

Noguchi obtained pure cultures of spirochaetae. See also his later papers in the same journal, 1912, 16, 199-210, 620-28.

1949 CE

#5515

Pure granulomatous nocardiosis: a new fungus disease distinguished by intracellular parasitism. A description of a new disease in man due to a hitherto undescribed organism, Nocardia intracellularis, n.sp., including a study of the biological and pathogenic properties of this species.

Nocardiosis described.

1995 CE

#11997

Purification and characterization of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis.

Andersen and colleagues found that a protein fraction obtained from M. tuberculosis was immunologically active in mice, suggesting that it was one of the proteins recognized by T cells. In this paper the authors ident…

1855 CE

#5876

Quelques considérations sur la nature de l’ophthalmie dite militaire, par rapport à son apparition dans l’armée danoise depuis 1851.

Description of trachoma.

1906 CE

#2563

Quelques remarques sur le lait aigri.

Metchnikoff researched the effect of lactic acid produced by Lactobacilli on other non-desirable bacteria in the digestive tract. He thus expanded Döderlein's (No. 6279) concept of "normal flora" beyond the vagin…