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DULBECCO, Renato (1914 – 2012)

DULBECCO, Renato (1914 – 2012)

1914 – 2012

6 entries in the GMN corpus.

Image source Renato_Dulbecco.jpg : Unknown, gift Dr. Dulbecco derivative work: Materialscientist ( talk ) · This file was derived from: Renato Dulbecco.jpg : · Public domain

1949 CE

#2526.1

Genetic recombinations leading to production of active bacteriophage from ultraviolet inactivated bacteriophage particles.

In 1969 Luria shared the Nobel Prize in Physiology or Medicine in with Delbrück (No. 2578.5) and A. D. Hershey (No. 256) "for their discoveries concerning the replication mechanism and the genetic structure of vi…

1952 CE

#13999

Production of plaques in monolayer tissue cultures by single particles of an animal virus.

Following Max Delbruck's advice, Dulbecco visited the major centers of animal virus work in the US in order to discover a way to quantitatively assay animal viruses by a plaque technique, similar to the technique that…

1954 CE

#14000

Plaque formation and isolation of pure lines with poliomyelitis viruses.

Dulbecco and Vogt were the first to successfully grow the poliovirus in vitro. They were also able to plaque purify it-- an essential step for subsequent vaccine production.

1960 CE

#2660.13

Virus-cell interaction with a tumour-producing virus.

Polyomavirus (papovavirus) shown to be capable of transforming cells in culture. Full text from PubMedCentral at this link.

1968 CE

#13947

The integrated state of viral DNA in SV40-transformed cells.

Dulbecco and his group demonstrated that the infection of normal cells with certain types of viruses (oncoviruses) led to the incorporation of virus-derived genes into the host-cell genome, and that this event lead to…

1975 CE

#2660.27

From the molecular biology of oncogenic DNA viruses to cancer. Les Prix Nobel en 1975, pp. 172-80.

In 1975 Dulbecco shared the Nobel Prize in Physiology or Medicine with David Baltimore and Howard Martin Temin "for their discoveries concerning the interaction between tumour viruses and the genetic material of the c…