Facets

1950 CE

#2352

A new and practical B.C.G. skin test (the B.C.G. scarification test) for the detection of the total tuberculous allergy.

1891 CE

#10598

A practical treatise on diseases of the skin

The first systematic treatise on dermatology published in America. Piffard was a pioneer of "indoor" magnesium flashlight photography, and took most of the 50 photographs reproduced in this book by this technique. Dig…

1950 CE

#2660.2

A sensitive directional gamma-ray detector.

Directional scintillation detector probe. Cassen assembled the first automated scanning system, comprised of a motor driven scintillation detector coupled to a relay printer. The scanner was initially used to image th…

1830 CE

#2611

A short tract on the formation of tumours, and the peculiarities that are met with in the structure of those that have become cancerous; with their mode of treatment.

Contains the first illustrations of microscopic sections of cancer; however, Home drew no worthwhile conclusion from his microscopic studies. Digital facsimile from the Internet Archive at this link.

1919 CE

#3922

A system of blood analysis.

Folin–Wu test for blood sugar.

1940 CE

#2010.2

Acceleration of electrons by magnetic induction.

Betatron. Continued as Kerst, "The acceleration of elecrons by magnetic induction," Phys. Rev., 60 (1941) 47-52. Digital facsimile of the 1941 paper at this link.

2003 CE

#10244

ArtandMedicine.com.

http://www.artandmedicine.com/Index.html A highly personal but in all aspects extraordinary website/blog on the history of medical photography in the form of what Rowley calls his Cabinet Journal.

1872 CE

#13212

Autumnal catarrh (Hay fever) with three maps.

Wyman conducted experiments that convinced him that ragweed was a cause of hay fever. He then collected data from correspondents and published the first pollen maps of the U.S. so that sufferers could plan vacations i…

1913 CE

#13264

Beiträge zur Pathologie und Klinik der Mammacarcinome.

In a study of 3,000 mastectomies, Salomon compared X-rays of the beasts (mammograms) to the actual removed tissue, paying close attention to microcalcifications. In doing so he was able to establish the difference in …

1904 CE

#2561

Blood immunity and blood relationship, a demonstration of certain blood relationships amongst animals by means of the precipitin test for blood.

2014 CE

#13738

Cancer concepts: A guidebook for the non-oncologist.

https://escholarship.umassmed.edu/cancer_concepts/8/ The first interactive Open access (OA) electronic textbook on any medical subject. This eBook was designed for first year medical students. Order of authorship on t…

1989 CE

#10340

Cancer mapping, edited by Peter Boyle, Calum S. Muir, and Ekkehard Grundmann.

The first chapter, by G. M. Howe is "Historical evolution of disease mapping in general and specifically of cancer mapping." The book as a whole discusses the wide range of cancer maps and atlases in U.S., Europe and …

2017 CE

#10555

Cancer, radiation therapy, and the market.

1902 CE

#2625.1

Cancroid des rechten Handrückens.

Frieben reported the carcinogenic effect of x-rays in man.

1868 CE

#6872

Clinique photographique de l'hôpital Saint-Louis.

The first French dermatologic book illustrated with photographs. Originally issued in fascicules, 1867-68. The first edition includes 49 or 50 albumin photographs; second edition, entitled Clinique photographique des …

1956 CE–1960 CE

#86.4

Collected papers of Paul Ehrlich. Compiled and edited by F. Himmelweit. 3 vols.

Vol. I: Histology, biochemistry, and pathology, Vol. 2: Immunology and cancer research; Vol. 3: Chemotherapy. Most texts are in German. English translations are also published when available. The set includes new Engl…

1823 CE

#1492.1

Commentatio de examine physiologico organi visus et systematis cutanei.

Purkynĕ was first to examine the interior of the human eye and the dog eye, using only a candle and a concave spherical lens. He thus invented the ophthalmoscope three decades before Helmholtz (1851; No. 5866). Reprin…

1976 CE

#14222

Correlation of glucose regulation and hemoglobin AIc in diabetes mellitus.

The authors studied 5 diabetic patients and first realized that A1c was an ideal index to reveal the overall control of a patient’s blood sugar over the past several months before a doctor’s visit. They we…

1844 CE–1845 CE

#267.1

Cours de microscopie. 1 vol. and atlas.

Donne's and Foucault's work was the first biomedical textbook to be illustrated with images made from photomicrographs, in this case daguerreotypes of blood cells. Among its noteworthy images are the first microphotog…

1897 CE

#2002

Demonstration eines mit Röntgenstrahlen behandelten Falles von Naevus pigmentosus pilosus.

First use of x rays for deep irradiation therapy.

1913 CE

#5066

Die Diphtherietoxin – Hautreaktion des Menschen als Vorprobe der prophylaktischen Diphtherieheilseruminjektion.

Schick developed his test for use as an indication as to whether or not prophylactic injections of antitoxin are necessary in children already exposed to diphtheria. English translation in J. Mt. Sinai Hosp., 1938, 5,…

1902 CE

#2625

Die Lehre von den Geschwülsten. 2 vols.

“With this book the microscopical epoch in the evolution of the knowledge of cancer may be said to have been brought to a close” (Haagensen).

1927 CE

#2008

Discordance des effets des rayons X, d’une part dans la peau, d’autre part dans le testicule, par le fractionnement de la dose: diminution de l’efficacité dans la peau, maintien de l’efficacité dans le testicule.

Dose fractionation.

1937 CE

#12832

Electrophoresis of serum globulin. II- Electrophoretic analysis of normal and immune sera.

Tiselius showed that an antibody that he produced in a rabbit by immunizing it with albumin (ovalbumin) was clearly located in the gamma globulin fraction. He summarized the paper with this statement: "Investigation o…

1971 CE

#12601

Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G.

Perlmann (principal investigator) and Engvall conceptualized and developed the very commonly used enzyme-lined immunosorbent assay (ELISA) that uses antibodies to detect proteins and other different immunogens. The as…

1919 CE–1920 CE

#3850

Epinephrin hypersensitiveness test in the diagnosis of hyperthyroidism.

Goetsch devised a skin reaction test for use in the diagnosis of hyperthyroidism

1979 CE

#13980

Expression in Escherichia coli of chemically synthesized genes for human insulin (plasmid construction / lac operon / fused proteins / radioimmunoassay / peptide purification).

Working at Genentech, Kleid and Goeddel and colleagues were the first scientists to apply genetic engineering techniques, incorporating chemically synthesized DNA encoding human insulin into E. coli, that expressed, a…

1926 CE

#2650

Haemagglutinegehalte van het bloedserum bij carcinoompatiënten.

Bendien test for the diagnosis of cancer. He published books in German and English on this subject in 1931. Modification by E. C. Lowe, Brit. med. J., 1932, 2, 1060.

1891 CE–1893 CE

#534.68

Human monstrosities. 4 vols.

The first large work on the subject illustrated primarily by photographs of specimens, and one of the last to use to the term "monster" as a medical descriptor. Digital facsimile of the 4 volumes from the Internet Arc…

1886 CE–1890 CE

#7744

Klinicheskii sbornik po dermatologii i sifilologii. 4 vols.

Mansurov was the first dermatologist in Russia, and one of the first physicians to use photography systematically in medical illustration. This was a periodical, illustrated with original photographs, of which Manusro…

1908 CE

#5065

Kutanreaktion beil Impfung mit Diphtherietoxin.

The Schick test for the determination of susceptibility to diphtheria.

1911 CE

#2637.1

Le cancer expérimental.

Experimental production of malignant tumors by means of x rays.

2013 CE

#9336

Life atomic: A history of radioisotopes in science and medicine.

1901 CE

#4003

Note sur le traitement du lupus érythémateux par des applications de radium.

First application of radium in the treatment of lupus.

1940 CE

#3099

Nuclear physics and therapy: preliminary report on a new method for the treatment of leukemia and polycythemia.

Radio-phosphorus in treatment of leukemia.

1919 CE

#2440

On the value of a skin reaction to a suspension of leprous nodules.

Mitsuda (lepromin) reaction. English translation by the author in Int. J. Leprosy, 1953, 21, 347-58.

1880 CE

#3996

Photographic illustrations of skin diseases.

Fox, who was Professor of Dermatology in New York, produced a valuable atlas of skin diseases.

1871 CE–1872 CE

#10585

Photographic review of medicine and surgery. A bi-monthly illustration of interesting cases, accompanied by notes. Edited by F.F. Maury [and] L.A. Duhring. Vols. 1 & 2 (All published).

The leading 19th century American publication of artistic medical photography. Each of the two volumes includes 24 mounted photographs. The photographs ilustrate cases of unusual and extreme disease, such as gross def…

1865 CE

#6873

Photographs (coloured from life) of the diseases of the skin.

The first dermatologic publication illustrated with photographs.

1892 CE

#2545.1

Practical results of bacteriological researches.

Sternberg demonstrated that the serum of an animal recovered from vaccinia possesses the property of neutralizing the activity of the causative virus. His test was readily adaptable for use in various host-systems.

1946 CE

#9338

Radioactive iodine therapy: Effect on functioning metastases of adenocarcinoma of the thyroid.

Seidlin and Marinelli described the first successful treatment of a patient with thyroid cancer metastases using radioiodine (I-131). This paper demonstrated the potential of nuclear medicine as a medical specialty.

1993 CE

#7182

Radiological oncologists: The unfolding of a medical specialty.

1896 CE

#2550

Recherches de la réaction agglutinante dans le sang et le sérum desséchés des typhiques et dans la sérosité des vesicatoires.

Developing the work of Gruber and Durham, Widal noted that a patient’s serum could be tested with bacteria of known type and his disease identified by this means. They demonstrated specific agglutinins in the bl…

1897 CE

#10597

Skin diseases of children. With twelve photogravure and chromographic plates, and sixty illustrations in the text.

Digital facsimile from the Internet Archive at this link.

1939 CE

#3098

Studies on leukemia with the aid of radioactive phosphorus.

Therapeutic use of radioactive isotopes for the treatment of leukemia. John H. Lawrence was the brother of Ernest Orlando Lawrence, inventor of the cyclotron; John Lawrence also worked at the Lawrence Berkeley Nationa…

1901 CE

#2553

Sur l’existence de substances sensibilisatrices dans la plupart des sérums antimicrobiens.

The Bordet–Gengou complement-fixation reaction is the basis of many tests for infection, notably the Wassermann test for syphilis, and reactions for gonococcus infection, glanders, hydatid disease. English trans…

1896 CE

#2001

Sur les radiations émises par phosphorescence.

The discovery of radioactivity – research stimulated by Roentgen’s discovery of x rays. In 1903 Becquerel received half of the Nobel Prize in Physics 1903 "in recognition of the extraordinary services he h…

1898 CE

#2003

Sur une substance nouvelle radio-active, contenue dans la pechblende.

The Curies, studying the radioactivity of minerals containing uranium and thorium, isolated from pitchblend a substance which they called radium and which they showed to possess an astonishing degree of radioactivity.…

1904 CE

#4004

Surla radiothérapie des teignes.

Sabouraud’s method of radiological treatment of ringworm.

1837 CE

#539

Symbolae ad anatomiam villorum intestinalium, imprimis eorum epithelii et vasorum lacteorum.

Henle first described the epithelia of the skin and intestines, and defined the structure and function of columnar and ciliated epithelium. He applied the term “epithelium” to all mucous membranes in the b…