Facets

1953 CE

#1175.3

The synthesis of an octapeptide amide with the hormonal activity of oxytocin.

Synthesis of oxytocin. With C. Ressler, J. M. Swan, C. W. Roberts, P. G. Katsoyannis, and S. Gordon. In 1955 Vigneaud was awarded the Nobel Prize in Chemistry "for his work on biochemically important sulphur compounds…

1951 CE

#13595

The technique of free skin grafting in mammals.

This "paper facilitated the later discovery of `actively acquired tolerance' and the definition of the principal laws of transplantation tolerance. Thus, it was in a series of classic experiments (stemming from this J…

1937 CE

#5467

The use of yellow fever virus modified by in vitro cultivation for human immunization.

Immunization without the use of immune serum. In 1951 Theiler was awared the Nobel Prize in Physiology or Medicine "for his discovery of an effective vaccine against yellow fever." This was the first Nobel Prize award…

1982 CE

#14266

Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

In 1982 Allison discovered the T-cell receptor. Order of authorship in the original publication: Allison, Bloch, McIntyre.

1936 CE

#1153

Über Bestandteile der Nebennieren-Rinde. VI. Trennungsmethoden sowie Isolierung der Substanzen Fa, H, und j.

Isolation of Compound Fa, identical with Compounds E and F. "In the mid-1930s Edward Kendall and Tadeus Reichstein succeeded in isolating and analyzing the composition of a number of similar hormones derived from the …

1934 CE

#1201

Über die Synthese des Testikelhormons (Androsteron) und Stereoisomerer desselben durch Abbau hydrierter Sterine.

First complete synthesis of a sex hormone (androsterone). With M. W. Goldberg, J. Meyer, H. Brüngger, and E. Eichenberger. In 1939 Ruzicka shared the 1939 Nobel Prize in Chemistry with Butenandt (No. 1195) "for h…

1890 CE

#2544

Ueber das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei Thieren.

Antitoxins and their immunizing powers were discovered when Behring and Kitasato published their paper dealing with immunity to tetanus and diphtheria. This work laid the foundation of all future treatment with antito…

1931 CE

#1195

Ueber die chemische Untersuchung der Sexualhormone.

The male sex hormone, androsterone, was isolated in crystalline form by Butenandt. In 1939 Butenandt received half of the Nobel Prize in Chemistry "for his work on sex hormones." The other half was awarded to Leopold …

1913 CE

#2640

Untersuchungen über eine Nematode (Spiroptera sp. n.) und deren Fähigkeit papillomatöse und carcinomatose Geschwulstbildungen im Magen der Ratte hervorzurufen.

Fibiger demonstrated that the roundworm, which he called Spiroptera carcinoma (but is correctly named Gongylonema neoplasticum), could cause stomach cancer (squamous cell carcinoma) in rats and mice. His experimental …

1970 CE

#2660.22

Viral RNA-dependent DNA polymerase: RNA-dependent DNA polymerase in virions of RNA tumour viruses.

In 1970 Baltimore and Temin discovered that certain viruses that have their genes in the form of RNA can copy the RNA "backward" into DNA in infected cells. The enyzme, reverse transcriptase, enables the manufacture o…

1792 CE

#6358

Von Menschen ohne Haare und Zähne.

Hereditary ectodermal dysplasia first described. Digital facsimile from Google Books at this link.