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7 entries match Professions & Education [M01 / N02] · Chemistry & Biochemistry [K01.900.200] · Women & Gender [K01.700.500]
2012 CE
#11844
A programmable dual RNA-guided DNA endonuclease in adaptive bacterial immunity.
Order of authorship in the original publication: Jinek, Chylinski, Fonfar, Hauer, Doudna, Charpentier. Doudna, Charpentier and colleagues showed for the first time that the CRISPR evolutionary immune tool of bacteria …
1934 CE
#9340
I. Un nouveau type de radioactivité. II. Séparation chimique des nouveaux radioéléments émetteur d’électrons positifs.
Discovery of artificially produced radionuclides or radioisotopes. In February 1934, the Joliot-Curies reported the first artificial production of radioactive material after discovering radioactivity in aluminum foil …
1952 CE
#3108.2
Studies on condensed pyrimidine system. IX. The synthesis of some 6-substituted purines.
Synthesis of 6-mercaptopurine. In 1988 Gertrude Elion shared the Nobel Prize in Physiology or Medicine with George Hitchings and Sir James Black “for their discoveries of important principles for drug treatment.…
1898 CE
#2003
Sur une substance nouvelle radio-active, contenue dans la pechblende.
The Curies, studying the radioactivity of minerals containing uranium and thorium, isolated from pitchblend a substance which they called radium and which they showed to possess an astonishing degree of radioactivity.…
1955 CE
#6928
The crystal structure of the hexacarboxylic acid derived from B12 and the molecular structure of the vitamin.
The final structure of vitamin B12. With J. Pickworth, J.H. Robertson, K.N. Trueblood, R.J. Prosen, J. G. White. In 1964 Hodgkin was awarded the Nobel Prize in Chemistry "for her determinations by X-ray techniques of …
1981 CE
#14224
The crystallization of ribsomal proteins from the 50 S subunit of the Escherichia coli and Bacillus stearothermophilus ribosome.
The authors crystallized fragments of the 50S subunit of a thermophile bacterium’s ribosome to 3 angstroms resolution. Order of authorship in the original publication: Appelt, Dyck, et al., Yonath. Digital facsi…
1993 CE
#14341
Tuning the activity of an enzyme for unusual environments: Sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide.
Arnold introduced a biochemical molecule manipulating technique to mimic the process of natural selection in creating new enzymes adapted to a specific catalytic reaction. She directed evolution of subtilisin E to obt…