On arrested cerebral development, with special reference to its cortical pathology.

Sachs described the cerebral changes in amaurotic familial idiocy. Earlier, Tay (No. 5918) had recorded the ocular manifestations of this condition, which became known as “Tay-Sachs’s disease”. Two further papers on the subject by Sachs are in the same journal, 1892, 17, 603-07; 1896, 21, 475-79.