HOPKINS, Sir Frederick Gowland (1861 – 1947)

1892 CE

#718

On the estimation of uric acid in the urine: a new process by means of saturation with ammonium chloride.

Hopkins’s method of estimating uric acid in urine.

1901 CE

#723

A contribution to the chemistry of proteids. I. A preliminary study of a hitherto undescribed product of tryptic digestion.

Isolation of tryptophan.

1906 CE

#1044

The analyst and the medical man.

Hopkins predicted the existence of vitamins as early as 1906. He fed animals a diet of zein which failed to maintain growth; however, the animals grew at once when casein was substituted. He concluded that “in t…

1906 CE

#732

The importance of individual amino-acids in metabolism.

Demonstration of the importance of tryptophan in diet. The pioneer work of Hopkins led eventually to the discovery of vitamins.

1907 CE

#733

Lactic acid in amphibian muscle.

Explanation of the production of lactic acid in normal muscular contraction.

1912 CE

#1048

Feeding experiments illustrating the importance of accessory factors in normal dietaries.

In 1929 Hopkins shared the Nobel Prize in Physiology or Medicine with Eijkman "for his discovery of the growth-stimulating vitamins."

1921 CE

#745

On an autoxidisable constituent of the cell.

Isolation of glutathione.