HEIDELBERGER, Michael (1888 – 1991)
1888 – 1991
3 entries in the GMN corpus.
Image source photograph by Harold Low, "Gift. Dr. Heidelberger." · Images from the History of Medicine (NLM) , Order No.: B014461 · Public domain
1919 CE
#1907
Chemotherapy of trypanosome and spirochete infections. Chemical series. I. N-phenylglycineamide-p-arsonic acid.
Introduction of tryparsamide.
1923 CE–1924 CE
#2573.2
The soluble specific substance of pneumococcus.
Heidelberger, Avery, and their colleagues made a chemical study of the antigenic constituents of the pneumococcus, separating the polysaccharide antigens.
1929 CE
#2576.01
A quantitative study of the precipitin reaction between Type III pneumococcus polysaccharide and purified homologous antibody.
Heidelberger and Kendall adapted the precipitin reaction to permit the quantitative measurement of antibody and antigen. This established the principle of quantitative immunochemistry.