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PUGH, Christopher W.

1 entries in the GMN corpus.

1999 CE

#14270

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.

The focus of both Peter Ratcliffe’s and William Kaelin’s work, for which they shared the Nobel Prize with Gregg Semenza, was the relationship between pVHL and HIF. This led to an increased understanding of…