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Garrison-Morton-Norman History of Medicine
GADDUM, Sir John Henry (1900 – 1965)

GADDUM, Sir John Henry (1900 – 1965)

1900 – 1965

3 entries in the GMN corpus.

Image source Josef Donnerer, Pharmakologisches Institut Graz · This image has been extracted from another file · CC BY-SA 3.0

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1926 CE

#1917

The action of adrenalin and ergotamine on the uterus of the rabbit.

GADDUM, Sir John Henry (1900 – 1965)
GADDUM, Sir John Henry (1900 – 1965)

Gaddum produced concentration-effect curves of antagonistic drugs, showing the dose-ratio linearly related to antagonistic concentration. See also No. 1925.1

1934 CE

#1352

The chemical transmitter at synapses in a sympathetic ganglion.

FELDBERG, Wilhelm Siegmund (1900 – 1993)
FELDBERG, Wilhelm Siegmund (1900 – 1993)
GADDUM, Sir John Henry (1900 – 1965)
GADDUM, Sir John Henry (1900 – 1965)

These workers produced evidence that a chemical agent (acetylcholine) appears in the transfer of nerve impulses from neuron to neuron in sympathetic ganglia.

1937 CE

#1925.1

The quantitative effect of antagonistic drugs

GADDUM, Sir John Henry (1900 – 1965)
GADDUM, Sir John Henry (1900 – 1965)

Gaddum was the first to formulate the theory of competitive drug antagonism. See also No. 1917.