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Historical Bibliography Updated: July 20, 2022

A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis.

Publication Details

Nature, 163, 676-7. 1949 CE.

The Barr body, " the inactive X chromosome in a female somatic cell,[2]  rendered inactive in a process called lyonization, in those species in which sex is determined by the presence of the Y (including humans) or W chromosome rather than the diploidy of the X. The Lyon hypothesis states that in cells with multiple X chromosomes, all but one are inactivated during mammalian embryogenesis.[3] This happens early in embryonic development at random in mammals,[4] except in marsupials and in some extra-embryonic tissues of some placental mammals, in which the father's X chromosome is always deactivated.[5] (Wikipedia article on Murray Barr, accessed 3-2020). See also Anat. Rec., 1952, 112, 709-12, and Surg. Gynec. Obstet., 1953, 96, 641-8.

Catalog MetadataReference Information
Entry Number#255.5
Permanent Linkhttps://staging.historyofmedicine.com/entry/8694
Author Bio LinkWikipedia ↗
External URLa-morphological-distinction-between-neurones-of-the-male-and-female-and-the-behaviour-of-the-nucleolar-satellite-during-accelerated-nucleoprotein-synthesis

Geographic Context

Mentioned in annotation: Lyon