Yellow fever, considered in its historical, pathological, etiological, and therapeutical relations: including a sketch of the disease as it has occurred in Philadelphia from 1699 to 1854, with an examination of the connections between it and the fevers known under the same name in other parts of temperate, as well as in tropical, regions. 2 vols.

The most important 19th century American monograph on yellow fever. La Roche’s work sketched the disease in its appearances from 1699 to 1854 at Philadelphia, which saw some of the worst yellow fever epidemics, and provided an excellent bibliography along with discussion of the pathology, aetiology and therapeutics of the disease. Digital facsimile from the National Library of Medicine, Internet Archive, at this link.