Die Bright’sche Nierenkrankheit.

Frerichs divided the progression of renal disease into three stages: initial hyperemia, fatty infiltration and exudation, and organization leading to fibrosis and atrophy. This is one of the earliest works on kidney disease to incorporate histological appearances. However, Frerichs did not recognize the primary involvement of the glomerulus in what later became known as glomerulonephritis. See No. 4212.