L’anatoxine diphtérique. Ses propriétés–ses applications.

In 1923 Ramon so modified the diphtheria toxin with formaldehyde that it lost its toxic properties while retaining its antigenic virtues. This modified “anatoxin” (toxoid) superseded toxin–antitoxin as an immunizing agent against diphtheria. Preliminary paper in C. R. Soc. Biol. (Paris), 1923, 89, 2-4.