Perforating inflammation of the vermiform appendix, with special reference to its early diagnosis and treatment.

A conclusive demonstration of the pathology and symptoms of disease of the vermiform appendix. Fitz invented the term “appendicitis”; his paper, which records 25 cases collected by himself, convinced physicians of the need to remove the appendix immediately if threatening symptoms did not subside within 24 hours. Reprinted in Med. Classics, 1938, 2, 459-91.