Penicillin treatment of early syphilis. A preliminary report.

Mahoney and colleagues introduced penicillin in treatment of syphilis. This was the report of the first four cases of patients with early stages of the disease. Digital facsimile of the version published in the the American Journal of Public Health from PubMedCentral at this link.

See John Parascandola, "John Mahoney and the introduction of penicillin to treat syphilis," Pharmacy in history, 43 (2001) 3-13.