A systematic treatise, historical, etiological, and practical, on the principal diseases of the interior valley of North America as they appear in the Causcasian, African, Indian, and Esquimaux varieties of Its population. 2 vols.

This classical contribution to the social / medical history of North America includes the most important work on the natural history of malaria published up to that time. Digital facsimile of vol. 1 from the Internet Archive at this link. Vol. 2 was posthumously published as 2nd series, edited by S. Hanbury Smith & F. G. Smith, Philadelphia, 1854. Digital facsimile of vol. 2 from Google Books at this link.