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Historical Bibliography Updated: June 16, 2026

Genetic control of the cell-division cycle in yeast 1. Detection of mutants.

Publication Details

Proc. Nat. Acad. Sci. (USA), 66, 352-59. 1970 CE.

This was the first paper to describe cdc mutants. The authors also coined the term 'execution point' — the stage in the cell cycle when the gene function is required. In this paper, three cdc genes were described, which paved the way for the identification of many more such genes, and for the discovery of the molecules and mechanisms controlling the cell

Order of authorship in the original publication: Hartwell, Culotti, Reid. Digital facsimile from PubMedCentral at this link .

Catalog MetadataReference Information
Entry Number#13933
Permanent Linkhttps://staging.historyofmedicine.com/entry/16229
Author Bio LinkWikipedia ↗
External URLgenetic-control-of-the-celldivision-cycle-in-yeast-1-detection-of-mutants