Il tabacco opera ... Nella quale si tratta dell'origine, historia, coltura, preparatione, qualità natura, virtà & uso in fumo, in polvere, in foglia, in lambitivo, et in medicina della pianta volgarmente detta tabacco, si discorre degl'vtili ch'arreca moderatamente preso, de i danni ch'apporta smoderatamente usato, e qual sia il vero e legitimo modo di prenderlo: trattato naturale, medico, morale & curioso.

Discusses the origin, history, cultivation, preparation, nature and virtues of tobacco, whether used for smoking, snuffing, chewing, etc. or for medicinal purposes (Waring). "The custom of smoking, its role in divination among the Indians, and its rapid spread throughout the world are dealt with, and several chapters are devoted to pipes... A long account of the subject of snuff is provided, and notice is taken of the papal interdictions of 1642 and 1650 against the use of tobacco in churches" (Arents). Digital facsimile from Google Books at this link.