Historical Bibliography Updated: June 16, 2026
The total synthesis of penicillin V.
Publication Details
J. Amer. chem. Soc., 29, 1262-1263. 1957 CE.
Sheehan and Henery-Logan reported the step by step synthesis of penicillin V (phenoxymethylpenicillin) and the cyclization of the beta lactam ring, key to creation of beta-lactam antibiotics.
(Thanks to Juan Weiss for this reference and its interpretation.)
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Thematic Classifications
| Catalog Metadata | Reference Information |
|---|---|
| Entry Number | #12633 |
| Permanent Link | https://staging.historyofmedicine.com/entry/14874 |
| Author Bio Link | Wikipedia ↗ |
| External URL | the-total-synthesis-of-penicillin-v |