DNA restriction and modification mechanisms in bacteria.

In this single author paper Boyer isolated, characterized and named the enzyme that Arber No. 12028 had observed and described in terms of its basic action on DNA. Boyer called it the “fi R-factor restriction endonuclease,” later to become EcoR1. He wrote, “The various restriction endonucleases with exclusive recognition capacities offer a unique probe for dissecting small genomes such as gamma, fd, polyoma and SV40. This work is now being undertaken in several labs, including the author’s."

Digital facsimile from annualreviews.org at this link.

(Thanks to Juan Weiss for this reference and its interpretation.)