Skip to main content
Historical Bibliography Updated: March 6, 2020

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus.

Publication Details

Nature Biotechnology, 34, 20-22. 2015 CE.

Order of authorship in the original publication: Whitworth, Rowland, Ewen, ... Prather. Using the CRISPR Cas molecular gene-editing tool, Prather and colleagues edited the gene that codes for the CD163 protein in adult male and female pigs gametes (sperm and egg) that acts similar to a receptor to which the Porcine reproductive and respiratory syndrome virus (PRRSV) attaches. This artificial genetic mutation created offsprint piglets that were resistant and immune to this panzootic infection which was previously lethal and incurable.

(Thanks to Juan Weiss for this reference and its interpretation.)

Catalog MetadataReference Information
Entry Number#11848
Permanent Linkhttps://staging.historyofmedicine.com/entry/14052
External URLgeneedited-pigs-are-protected-from-procine-reproductive-and-respiratory-syndrome-virus