Observations on the May-Bug, and its ravages on plum and other trees, and also on the means of preventing the mischief.

Griffth was probably the first American woman to publish in the sciences outside of materia medica and childcare. This article was probably her earliest non-geological publication. See Robt S. Cox, "A spontaneous flow: The geological contributions of Mary Griffith, 1772-1846," Earth Sciences History, 12, 187-195.