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Historical Bibliography Updated: December 21, 2019

Identification of a major co-receptor for primary isolates of HIV-1.

Publication Details

Nature, 381, 661-666. 1996 CE.

Order of authorship in the original publication: Deng, Liu, Ellmeier.... This paper was immediately followed in the same issue of Nature by:

Tatjana Dragic, Virginia Litwin, Graham P. Allaway et al. "HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5," Nature, 381, 667-673.

What was called CC-CKR-5 in the Dragic, Litwin, Allaway paper was later named CCR5. These two papers laid the theory and the foundation behind the purposeful and targeted search for bone marrow donors with this mutation that finally achieved success 13 years later in Gero Hütter et al GM 10775 ("Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation", 2009). 

(Thanks to Juan Weiss for this reference and its interpretation.)

Catalog MetadataReference Information
Entry Number#11365
Permanent Linkhttps://staging.historyofmedicine.com/entry/13564
Author Bio Linkwikipedia ↗
External URLidentification-of-a-major-coreceptor-for-primary-isolates-of-hiv1