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Historical Bibliography Updated: June 17, 2024

Spliced segments at the 5' terminus of adenovirus 2 late mRNA.

Publication Details

Proc. Nat. Acad. Sci. (USA), 74, 3171-3175. 1977 CE.

Discovery of introns simultaneously with Roberts, Chow, Broker (No. 11043). Sharp's electron microscopist, Berget, visualized the introns in the electron microscope. James D. Watson took note of the profound significance of the discovery and invited both groups to present their data at the Cold Spring Harbor Symposium that year. This helped solidify the discovery by both groups as "simultaneous."

In 1993 Sharp shared the Nobel Prize in Physiology or Medicine  with Richard J. Roberts "for their discoveries of split genes."

Digital facsimile from PubMedCentral at this link.

(Thanks for Juan Weiss for this entry and its interpretation.)

Catalog MetadataReference Information
Entry Number#11044
Permanent Linkhttps://staging.historyofmedicine.com/entry/13240
Author Bio LinkWikipedia ↗
External URLspliced-segments-at-the-5-terminus-of-adenovirus-2-late-mrna

Geographic Context

Mentioned in annotation: Cold Spring Harbor, NY