Tractatio med. curiosa, de ortu & occasasu transfusionis sanguins, qua haec, quae fit e bruto in brutum, a for medico penitus eliminatur; ila, quae e bruto in hominem peragitur....

The first detailed history of efforts at blood transfusion. Mercklin was one of the earliest writers to discuss the history, value, dangers, and methods of blood transfusion. He recognized and understood what we now call a transfusion reaction. Digital facsimile from Google Books at this link.