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Garrison-Morton-Norman History of Medicine

HUTCHISON, III, Clyde A.

1 entries in the GMN corpus.

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1978 CE

#13986

Mutagenesis at a specific position in a DNA sequence.

HUTCHISON, III, Clyde A. SMITH, Michael (1932 – 2000) & et al.

Smith and Hutchison introduced site-directed mutagenesis, or oligonucleotide-directed mutagenesis, into molecular biology, resolving the problem of how to determine the effect of a single mutant gene with efficiency. …