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Garrison-Morton-Norman History of Medicine
ZAMECNIK, Paul Charles (1912 – 2009)

ZAMECNIK, Paul Charles (1912 – 2009)

1912 – 2009

1 entries in the GMN corpus.

Image source Eric Koch for Anefo · GaHetNa (Nationaal Archief NL) (cropped) · CC BY 4.0

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1978 CE

#13969

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide (tridecamer deoxyribonucleotide/hybridization competitor/hybridon).

ZAMECNIK, Paul Charles (1912 – 2009)
ZAMECNIK, Paul Charles (1912 – 2009) STEPHENSON, Mary Louise (1921 – 2009)

Zamecnick and Stephenson reported the first example of specific inhibition of gene expression by an oligonucleotide when they demonstrated that a short oligonucleotide inhibited Rous sarcoma virus replication in cell …