LIU, David Ruchien (1973 – )
1973 –
3 entries in the GMN corpus.
Image source ServiceAT · Own work · CC BY-SA 4.0
2017 CE
#11865
Programmable base editing of A-T to G-C.
Order of authorship in the original publication: Gaudelli, Komor, Rees....Liu. Liu and colleagues developed an advanced CRISPR system that can edit pairings of DNA nucleotide bases Adenine and Thymine into Guanine and…
2019 CE
#11866
Search-and-replace genome editing without double-stranded breaks or donor DNA.
Order of authorship in the original publication: Anzalone, Randolph, Davis....Liu. Liu and colleagues modified the CRISPR tool to create the "prime editing" or precise genome editing technique. Working with human and …
2021 CE
#14218
In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice.
Using the base editor enzyme developed by Liu (GM11865), the authors report that they can “correct the pathogenic HGPS mutation in cultured fibroblasts derived from children with progeria and in a mouse model of…